DPPA2

 

Full name: developmental pluripotency associated 2 Alias Symbol: PESCRG1|CT100
Type: protein-coding gene Cytoband: 3q13.13
Entrez ID: 151871 HGNC ID: HGNC:19197 Ensembl Gene: ENSG00000163530 OMIM ID: 614445
Drug and gene relationship at DGIdb

 

Expression of DPPA2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 DPPA2 151871 240301_at 0.1324 0.5547
GSE26886 DPPA2 151871 240301_at 0.0061 0.9636
GSE45670 DPPA2 151871 240301_at 0.2536 0.3246
GSE63941 DPPA2 151871 240301_at 0.2659 0.6123
GSE77861 DPPA2 151871 240301_at -0.2315 0.0553
TCGA DPPA2 151871 RNAseq 5.1634 0.0005

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by DPPA2 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of DPPA2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 DPPA2 151871 17 1 12
GSE20123 DPPA2 151871 16 1 13
GSE43470 DPPA2 151871 18 1 24
GSE46452 DPPA2 151871 12 6 41
GSE47630 DPPA2 151871 16 6 18
GSE54993 DPPA2 151871 2 5 63
GSE54994 DPPA2 151871 28 5 20
GSE60625 DPPA2 151871 0 6 5
GSE74703 DPPA2 151871 15 1 20
GSE74704 DPPA2 151871 13 1 6
TCGA DPPA2 151871 50 8 38

Total number of gains: 187; Total number of losses: 41; Total Number of normals: 260.  

 

Somatic mutations of DPPA2:

 

Generating mutation plots.

 

Highly correlated genes for DPPA2:

 

Showing all 10 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
DPPA2ADAM120.641757303
DPPA2LINC002050.623263303
DPPA2PRELID10.603705303
DPPA2GAD10.583697303
DPPA2OR10H10.574203403
DPPA2TRABD2A0.573309303
DPPA2FAM131C0.571563303
DPPA2DAO0.569325303
DPPA2FAM207A0.539592403
DPPA2STK4-AS10.528356303

For details and further investigation, click here