PRELID1

 

Full name: PRELI domain containing 1 Alias Symbol: CGI-106|PX19|PRELI
Type: protein-coding gene Cytoband: 5q35.3
Entrez ID: 27166 HGNC ID: HGNC:30255 Ensembl Gene: ENSG00000169230 OMIM ID: 605733
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of PRELID1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PRELID1 27166 223032_x_at 0.3175 0.3433
GSE26886 PRELID1 27166 223032_x_at -0.3961 0.1852
GSE45670 PRELID1 27166 223032_x_at 0.0719 0.7572
GSE63941 PRELID1 27166 223032_x_at 1.0683 0.0110
GSE77861 PRELID1 27166 223032_x_at -0.3037 0.1915
GSE97050 PRELID1 27166 A_23_P79161 0.3671 0.1880
SRP007169 PRELID1 27166 RNAseq -1.8865 0.0000
SRP008496 PRELID1 27166 RNAseq -1.8361 0.0000
SRP064894 PRELID1 27166 RNAseq -0.1607 0.5526
SRP133303 PRELID1 27166 RNAseq -0.0638 0.6971
SRP159526 PRELID1 27166 RNAseq -0.2537 0.2731
SRP193095 PRELID1 27166 RNAseq -0.4327 0.0015
SRP219564 PRELID1 27166 RNAseq -0.0102 0.9787
TCGA PRELID1 27166 RNAseq 0.0511 0.4238

Upregulated datasets: 1; Downregulated datasets: 2.  


 

Survival by PRELID1 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of PRELID1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PRELID1 27166 2 13 15
GSE20123 PRELID1 27166 2 13 15
GSE43470 PRELID1 27166 1 11 31
GSE46452 PRELID1 27166 0 27 32
GSE47630 PRELID1 27166 1 20 19
GSE54993 PRELID1 27166 10 2 58
GSE54994 PRELID1 27166 2 17 34
GSE60625 PRELID1 27166 1 0 10
GSE74703 PRELID1 27166 1 7 28
GSE74704 PRELID1 27166 1 6 13
TCGA PRELID1 27166 8 34 54

Total number of gains: 29; Total number of losses: 150; Total Number of normals: 309.  


 

Somatic mutations of PRELID1:

 

Generating mutation plots.

 

Highly correlated genes for PRELID1:

 

Showing top 20/408 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PRELID1PSMD30.848406303
PRELID1MAPK60.833248303
PRELID1GPR1320.831102303
PRELID1MED270.805624303
PRELID1TMEM2080.80023303
PRELID1MCM100.794146303
PRELID1USP50.780732303
PRELID1MFSD30.779321404
PRELID1SH3BGRL30.778572404
PRELID1YARS20.769723303
PRELID1COASY0.766441303
PRELID1PREB0.76562303
PRELID1TMEM2140.764992303
PRELID1FAM89B0.758923303
PRELID1UBA520.758567303
PRELID1TEAD40.756895303
PRELID1NUDT50.756741303
PRELID1DARS20.754268303
PRELID1CDCA40.753861303
PRELID1DHX80.75222303

For details and further investigation, click here