| Full name: D-amino acid oxidase | Alias Symbol: DAMOX|DAAO | ||
| Type: protein-coding gene | Cytoband: 12q24.11 | ||
| Entrez ID: 1610 | HGNC ID: HGNC:2671 | Ensembl Gene: ENSG00000110887 | OMIM ID: 124050 |
| Drug and gene relationship at DGIdb | |||
Expression of DAO:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DAO | 1610 | 206878_at | 0.0867 | 0.7382 | |
| GSE20347 | DAO | 1610 | 206878_at | 0.0051 | 0.9633 | |
| GSE23400 | DAO | 1610 | 206878_at | -0.1328 | 0.0010 | |
| GSE26886 | DAO | 1610 | 206878_at | 0.1140 | 0.5371 | |
| GSE29001 | DAO | 1610 | 206878_at | -0.2538 | 0.0718 | |
| GSE38129 | DAO | 1610 | 206878_at | -0.0922 | 0.2326 | |
| GSE45670 | DAO | 1610 | 206878_at | 0.0913 | 0.2885 | |
| GSE53622 | DAO | 1610 | 130315 | -0.5764 | 0.0000 | |
| GSE53624 | DAO | 1610 | 1480 | -0.4618 | 0.0000 | |
| GSE63941 | DAO | 1610 | 206878_at | 0.2265 | 0.1520 | |
| GSE77861 | DAO | 1610 | 206878_at | -0.1283 | 0.1694 | |
| GSE97050 | DAO | 1610 | A_23_P139635 | -0.1228 | 0.6212 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DAO expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DAO:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DAO | 1610 | 5 | 3 | 22 | |
| GSE20123 | DAO | 1610 | 5 | 4 | 21 | |
| GSE43470 | DAO | 1610 | 2 | 1 | 40 | |
| GSE46452 | DAO | 1610 | 9 | 1 | 49 | |
| GSE47630 | DAO | 1610 | 9 | 1 | 30 | |
| GSE54993 | DAO | 1610 | 0 | 5 | 65 | |
| GSE54994 | DAO | 1610 | 4 | 2 | 47 | |
| GSE60625 | DAO | 1610 | 0 | 0 | 11 | |
| GSE74703 | DAO | 1610 | 2 | 0 | 34 | |
| GSE74704 | DAO | 1610 | 2 | 2 | 16 | |
| TCGA | DAO | 1610 | 21 | 10 | 65 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of DAO:
Generating mutation plots.
Highly correlated genes for DAO:
Showing top 20/910 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DAO | GDF7 | 0.753036 | 3 | 0 | 3 |
| DAO | ZC3H10 | 0.743114 | 3 | 0 | 3 |
| DAO | NT5C1A | 0.733858 | 4 | 0 | 4 |
| DAO | TDGF1 | 0.733523 | 3 | 0 | 3 |
| DAO | SLC35F3 | 0.73239 | 3 | 0 | 3 |
| DAO | KRTAP6-1 | 0.731019 | 3 | 0 | 3 |
| DAO | RALYL | 0.72928 | 4 | 0 | 4 |
| DAO | VMO1 | 0.728475 | 3 | 0 | 3 |
| DAO | MAGEA8 | 0.726571 | 3 | 0 | 3 |
| DAO | OVGP1 | 0.726305 | 4 | 0 | 4 |
| DAO | SAMD4A | 0.720133 | 3 | 0 | 3 |
| DAO | CALML6 | 0.717482 | 3 | 0 | 3 |
| DAO | BCAN | 0.709919 | 6 | 0 | 6 |
| DAO | KCNA6 | 0.708166 | 3 | 0 | 3 |
| DAO | GPR78 | 0.703182 | 4 | 0 | 4 |
| DAO | TPRX1 | 0.701833 | 3 | 0 | 3 |
| DAO | TRAIP | 0.701742 | 3 | 0 | 3 |
| DAO | CLRN2 | 0.701515 | 3 | 0 | 3 |
| DAO | TEKT2 | 0.699997 | 4 | 0 | 4 |
| DAO | SYT13 | 0.69866 | 3 | 0 | 3 |
For details and further investigation, click here
