| Full name: G protein-coupled receptor 15 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q11.2 | ||
| Entrez ID: 2838 | HGNC ID: HGNC:4469 | Ensembl Gene: ENSG00000154165 | OMIM ID: 601166 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR15 | 2838 | 208524_at | -0.1493 | 0.4305 | |
| GSE20347 | GPR15 | 2838 | 208524_at | -0.0497 | 0.5945 | |
| GSE23400 | GPR15 | 2838 | 208524_at | -0.2011 | 0.0000 | |
| GSE26886 | GPR15 | 2838 | 208524_at | -0.5485 | 0.0024 | |
| GSE29001 | GPR15 | 2838 | 208524_at | -0.2295 | 0.0677 | |
| GSE38129 | GPR15 | 2838 | 208524_at | -0.1167 | 0.0570 | |
| GSE45670 | GPR15 | 2838 | 208524_at | 0.1082 | 0.3035 | |
| GSE53622 | GPR15 | 2838 | 26621 | -1.3968 | 0.0000 | |
| GSE53624 | GPR15 | 2838 | 26621 | -1.0950 | 0.0000 | |
| GSE63941 | GPR15 | 2838 | 208524_at | 0.1305 | 0.7047 | |
| GSE77861 | GPR15 | 2838 | 208524_at | -0.1588 | 0.1001 | |
| GSE97050 | GPR15 | 2838 | A_23_P6943 | -0.1921 | 0.6776 | |
| SRP064894 | GPR15 | 2838 | RNAseq | -0.9132 | 0.1011 | |
| SRP133303 | GPR15 | 2838 | RNAseq | -1.5327 | 0.0250 | |
| SRP159526 | GPR15 | 2838 | RNAseq | -0.8609 | 0.6929 | |
| SRP193095 | GPR15 | 2838 | RNAseq | -0.9140 | 0.0122 | |
| TCGA | GPR15 | 2838 | RNAseq | 0.9471 | 0.1337 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by GPR15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR15 | 2838 | 20 | 1 | 9 | |
| GSE20123 | GPR15 | 2838 | 19 | 1 | 10 | |
| GSE43470 | GPR15 | 2838 | 18 | 1 | 24 | |
| GSE46452 | GPR15 | 2838 | 12 | 6 | 41 | |
| GSE47630 | GPR15 | 2838 | 16 | 6 | 18 | |
| GSE54993 | GPR15 | 2838 | 2 | 5 | 63 | |
| GSE54994 | GPR15 | 2838 | 27 | 5 | 21 | |
| GSE60625 | GPR15 | 2838 | 0 | 6 | 5 | |
| GSE74703 | GPR15 | 2838 | 14 | 1 | 21 | |
| GSE74704 | GPR15 | 2838 | 14 | 1 | 5 | |
| TCGA | GPR15 | 2838 | 49 | 10 | 37 |
Total number of gains: 191; Total number of losses: 43; Total Number of normals: 254.
Somatic mutations of GPR15:
Generating mutation plots.
Highly correlated genes for GPR15:
Showing top 20/954 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR15 | CPA2 | 0.724663 | 3 | 0 | 3 |
| GPR15 | CYP2D6 | 0.702044 | 6 | 0 | 6 |
| GPR15 | APOBEC2 | 0.687736 | 3 | 0 | 3 |
| GPR15 | CST11 | 0.684578 | 3 | 0 | 3 |
| GPR15 | MVK | 0.681283 | 7 | 0 | 7 |
| GPR15 | CRISP1 | 0.680218 | 5 | 0 | 5 |
| GPR15 | SIRT3 | 0.672973 | 6 | 0 | 6 |
| GPR15 | OR51M1 | 0.670284 | 3 | 0 | 3 |
| GPR15 | KIR2DS2 | 0.668192 | 4 | 0 | 4 |
| GPR15 | FAM76A | 0.665958 | 3 | 0 | 3 |
| GPR15 | TNFSF11 | 0.665149 | 4 | 0 | 4 |
| GPR15 | E2F4 | 0.664084 | 6 | 0 | 5 |
| GPR15 | DRD5 | 0.663498 | 4 | 0 | 4 |
| GPR15 | ADH6 | 0.660757 | 7 | 0 | 6 |
| GPR15 | THEG | 0.659463 | 5 | 0 | 4 |
| GPR15 | GAS8 | 0.657825 | 7 | 0 | 5 |
| GPR15 | RGR | 0.6578 | 6 | 0 | 5 |
| GPR15 | SRPK3 | 0.65601 | 3 | 0 | 3 |
| GPR15 | GFOD2 | 0.655618 | 4 | 0 | 4 |
| GPR15 | ACR | 0.65502 | 4 | 0 | 4 |
For details and further investigation, click here
