FAM177B

 

Full name: family with sequence similarity 177 member B Alias Symbol: RP11-452F19.2|FLJ43505
Type: protein-coding gene Cytoband: 1q41
Entrez ID: 400823 HGNC ID: HGNC:34395 Ensembl Gene: ENSG00000197520 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of FAM177B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 FAM177B 400823 21125 -0.1318 0.1061
GSE53624 FAM177B 400823 21125 0.2163 0.0313
GSE97050 FAM177B 400823 A_33_P3367396 0.2367 0.5843
SRP133303 FAM177B 400823 RNAseq -1.7368 0.0005
TCGA FAM177B 400823 RNAseq -4.0329 0.0000

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by FAM177B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FAM177B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FAM177B 400823 10 0 20
GSE20123 FAM177B 400823 10 0 20
GSE43470 FAM177B 400823 7 0 36
GSE46452 FAM177B 400823 3 1 55
GSE47630 FAM177B 400823 15 0 25
GSE54993 FAM177B 400823 0 6 64
GSE54994 FAM177B 400823 16 0 37
GSE60625 FAM177B 400823 0 0 11
GSE74703 FAM177B 400823 7 0 29
GSE74704 FAM177B 400823 4 0 16
TCGA FAM177B 400823 45 3 48

Total number of gains: 117; Total number of losses: 10; Total Number of normals: 361.  

 

Somatic mutations of FAM177B:

 

Generating mutation plots.

 

Highly correlated genes for FAM177B:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FAM177BGPR1500.805735303
FAM177BSTAC30.764069303
FAM177BSP80.754087303
FAM177BCABP40.746684303
FAM177BZNF3290.743625303
FAM177BRNF320.708256303
FAM177BGPR320.682058303
FAM177BZNF8350.667332303
FAM177BMRGPRD0.657741303
FAM177BGRXCR20.64086303
FAM177BKCNQ10.599808303

For details and further investigation, click here