SP8

 

Full name: Sp8 transcription factor Alias Symbol: 
Type: protein-coding gene Cytoband: 7p21.1
Entrez ID: 221833 HGNC ID: HGNC:19196 Ensembl Gene: ENSG00000164651 OMIM ID: 608306
Drug and gene relationship at DGIdb

 

Expression of SP8:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SP8 221833 239743_at 0.0759 0.7709
GSE26886 SP8 221833 239743_at 0.2953 0.0287
GSE45670 SP8 221833 239743_at 0.0742 0.5298
GSE53622 SP8 221833 22298 0.0248 0.8273
GSE53624 SP8 221833 22298 -0.0163 0.8624
GSE63941 SP8 221833 239743_at 0.5264 0.0169
GSE77861 SP8 221833 239743_at 0.0579 0.7276
GSE97050 SP8 221833 A_33_P3250148 0.1664 0.3946
SRP159526 SP8 221833 RNAseq 6.4010 0.0000
TCGA SP8 221833 RNAseq 6.1022 0.0000

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by SP8 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SP8:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SP8 221833 16 2 12
GSE20123 SP8 221833 16 2 12
GSE43470 SP8 221833 4 0 39
GSE46452 SP8 221833 10 2 47
GSE47630 SP8 221833 9 1 30
GSE54993 SP8 221833 0 6 64
GSE54994 SP8 221833 20 2 31
GSE60625 SP8 221833 0 0 11
GSE74703 SP8 221833 4 0 32
GSE74704 SP8 221833 10 2 8
TCGA SP8 221833 56 5 35

Total number of gains: 145; Total number of losses: 22; Total Number of normals: 321.  

 

Somatic mutations of SP8:

 

Generating mutation plots.

 

Highly correlated genes for SP8:

 

Showing top 20/477 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SP8PAX20.788646303
SP8RIN10.782141303
SP8MAG0.780635303
SP8PNLIPRP10.770212303
SP8IGFALS0.767468303
SP8NLRP50.766685303
SP8ADAP10.764651404
SP8FAM177B0.754087303
SP8GPR1500.750744404
SP8ARVCF0.746367403
SP8IGFN10.746263303
SP8SSH30.736376303
SP8MGAT5B0.73095404
SP8ZIC10.727486303
SP8GPHA20.724978303
SP8CRYGA0.721045404
SP8RPP250.720674303
SP8FMR1NB0.717708303
SP8TMEM2350.716887303
SP8ZSWIM30.714732303

For details and further investigation, click here