GPR32

 

Full name: G protein-coupled receptor 32 Alias Symbol: RVDR1
Type: protein-coding gene Cytoband: 19q13.33
Entrez ID: 2854 HGNC ID: HGNC:4487 Ensembl Gene: ENSG00000142511 OMIM ID: 603195
Drug and gene relationship at DGIdb

 

Expression of GPR32:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GPR32 2854 221469_at -0.0342 0.8914
GSE20347 GPR32 2854 221469_at 0.0619 0.3030
GSE23400 GPR32 2854 221469_at -0.0207 0.6296
GSE26886 GPR32 2854 221469_at 0.1279 0.2112
GSE29001 GPR32 2854 221469_at -0.0611 0.6956
GSE38129 GPR32 2854 221469_at -0.0471 0.4304
GSE45670 GPR32 2854 221469_at 0.0159 0.8623
GSE53622 GPR32 2854 63719 0.2779 0.0001
GSE53624 GPR32 2854 63719 0.7083 0.0000
GSE63941 GPR32 2854 221469_at 0.0374 0.7792
GSE77861 GPR32 2854 221469_at 0.0504 0.6073
GSE97050 GPR32 2854 A_23_P142096 0.2562 0.2616
TCGA GPR32 2854 RNAseq 1.2164 0.5663

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GPR32 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GPR32:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GPR32 2854 3 4 23
GSE20123 GPR32 2854 3 3 24
GSE43470 GPR32 2854 4 11 28
GSE46452 GPR32 2854 45 1 13
GSE47630 GPR32 2854 9 6 25
GSE54993 GPR32 2854 17 4 49
GSE54994 GPR32 2854 4 14 35
GSE60625 GPR32 2854 9 0 2
GSE74703 GPR32 2854 4 7 25
GSE74704 GPR32 2854 3 1 16
TCGA GPR32 2854 14 19 63

Total number of gains: 115; Total number of losses: 70; Total Number of normals: 303.  


 

Somatic mutations of GPR32:

 

Generating mutation plots.

 

Highly correlated genes for GPR32:

 

Showing top 20/724 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GPR32C1QL20.827663303
GPR32MYO15B0.820362303
GPR32ABCC20.794993303
GPR32PABPN1L0.794267303
GPR32MS4A180.792172303
GPR32DCDC10.786242303
GPR32LHB0.782882303
GPR32OR2A50.780821303
GPR32LYZL20.764988303
GPR32MYO1A0.764756303
GPR32PSMB110.764581303
GPR32BSX0.762995303
GPR32LRRIQ30.762035303
GPR32PRSS380.759766303
GPR32BLACE0.757257303
GPR32TBC1D10B0.754133303
GPR32CHST100.753436303
GPR32C9orf1530.751479303
GPR32FBRSL10.749847303
GPR32LINC003020.749093303

For details and further investigation, click here