| Full name: glutaredoxin and cysteine rich domain containing 2 | Alias Symbol: DFNB101 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 643226 | HGNC ID: HGNC:33862 | Ensembl Gene: ENSG00000204928 | OMIM ID: 615762 |
| Drug and gene relationship at DGIdb | |||
Expression of GRXCR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | GRXCR2 | 643226 | 79594 | -0.0252 | 0.7883 | |
| GSE53624 | GRXCR2 | 643226 | 79594 | 0.2483 | 0.0052 | |
| GSE97050 | GRXCR2 | 643226 | A_33_P3421978 | -0.1966 | 0.5259 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GRXCR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRXCR2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRXCR2 | 643226 | 1 | 12 | 17 | |
| GSE20123 | GRXCR2 | 643226 | 1 | 12 | 17 | |
| GSE43470 | GRXCR2 | 643226 | 2 | 9 | 32 | |
| GSE46452 | GRXCR2 | 643226 | 0 | 27 | 32 | |
| GSE47630 | GRXCR2 | 643226 | 1 | 19 | 20 | |
| GSE54993 | GRXCR2 | 643226 | 9 | 1 | 60 | |
| GSE54994 | GRXCR2 | 643226 | 2 | 14 | 37 | |
| GSE60625 | GRXCR2 | 643226 | 0 | 0 | 11 | |
| GSE74703 | GRXCR2 | 643226 | 2 | 7 | 27 | |
| GSE74704 | GRXCR2 | 643226 | 1 | 7 | 12 | |
| TCGA | GRXCR2 | 643226 | 3 | 39 | 54 |
Total number of gains: 22; Total number of losses: 147; Total Number of normals: 319.
Somatic mutations of GRXCR2:
Generating mutation plots.
Highly correlated genes for GRXCR2:
Showing top 20/57 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRXCR2 | TRPM8 | 0.808517 | 3 | 0 | 3 |
| GRXCR2 | PRSS38 | 0.787172 | 3 | 0 | 3 |
| GRXCR2 | TXNDC2 | 0.777849 | 3 | 0 | 3 |
| GRXCR2 | KCNK3 | 0.76472 | 3 | 0 | 3 |
| GRXCR2 | SLC22A25 | 0.761611 | 3 | 0 | 3 |
| GRXCR2 | SHISA8 | 0.757092 | 3 | 0 | 3 |
| GRXCR2 | PLA2G12B | 0.755278 | 3 | 0 | 3 |
| GRXCR2 | C1QL2 | 0.750351 | 3 | 0 | 3 |
| GRXCR2 | DNAI1 | 0.746036 | 3 | 0 | 3 |
| GRXCR2 | EVX1 | 0.737842 | 3 | 0 | 3 |
| GRXCR2 | DCDC1 | 0.731933 | 3 | 0 | 3 |
| GRXCR2 | GRIK4 | 0.728027 | 3 | 0 | 3 |
| GRXCR2 | GIPR | 0.727192 | 3 | 0 | 3 |
| GRXCR2 | TSPAN11 | 0.725962 | 3 | 0 | 3 |
| GRXCR2 | DRD3 | 0.725344 | 3 | 0 | 3 |
| GRXCR2 | CABP4 | 0.724943 | 3 | 0 | 3 |
| GRXCR2 | MAG | 0.722839 | 3 | 0 | 3 |
| GRXCR2 | FBRSL1 | 0.721941 | 3 | 0 | 3 |
| GRXCR2 | PABPN1L | 0.716934 | 3 | 0 | 3 |
| GRXCR2 | RNF180 | 0.716735 | 3 | 0 | 3 |
For details and further investigation, click here
