Full name: family with sequence similarity 221 member B | Alias Symbol: | ||
Type: protein-coding gene | Cytoband: 9p13.3 | ||
Entrez ID: 392307 | HGNC ID: HGNC:30762 | Ensembl Gene: ENSG00000204930 | OMIM ID: |
Drug and gene relationship at DGIdb |
Expression of FAM221B:
Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
---|---|---|---|---|---|---|
GSE17351 | FAM221B | 392307 | 240871_at | -0.0404 | 0.9022 | |
GSE26886 | FAM221B | 392307 | 240871_at | 0.1071 | 0.4416 | |
GSE45670 | FAM221B | 392307 | 240871_at | -0.0600 | 0.5067 | |
GSE53622 | FAM221B | 392307 | 149500 | -0.0352 | 0.5364 | |
GSE53624 | FAM221B | 392307 | 149500 | 0.1743 | 0.0056 | |
GSE63941 | FAM221B | 392307 | 240871_at | 0.0669 | 0.6869 | |
GSE77861 | FAM221B | 392307 | 240871_at | -0.0987 | 0.3616 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM221B expression:
Note: Click image to view full size file.
Copy number change of FAM221B:
Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
---|---|---|---|---|---|---|
GSE15526 | FAM221B | 392307 | 3 | 12 | 15 | |
GSE20123 | FAM221B | 392307 | 3 | 12 | 15 | |
GSE43470 | FAM221B | 392307 | 3 | 10 | 30 | |
GSE46452 | FAM221B | 392307 | 6 | 15 | 38 | |
GSE47630 | FAM221B | 392307 | 1 | 20 | 19 | |
GSE54993 | FAM221B | 392307 | 6 | 0 | 64 | |
GSE54994 | FAM221B | 392307 | 5 | 12 | 36 | |
GSE60625 | FAM221B | 392307 | 0 | 0 | 11 | |
GSE74703 | FAM221B | 392307 | 2 | 7 | 27 | |
GSE74704 | FAM221B | 392307 | 0 | 10 | 10 | |
TCGA | FAM221B | 392307 | 17 | 44 | 35 |
Total number of gains: 46; Total number of losses: 142; Total Number of normals: 300.
Somatic mutations of FAM221B:
Generating mutation plots.
Highly correlated genes for FAM221B:
Showing all 15 correlated genes with mean PCC>0.5.
Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
---|---|---|---|---|---|
FAM221B | ZNF517 | 0.66213 | 3 | 0 | 3 |
FAM221B | BARHL1 | 0.632433 | 3 | 0 | 3 |
FAM221B | CDH7 | 0.629522 | 3 | 0 | 3 |
FAM221B | C10orf71-AS1 | 0.613016 | 3 | 0 | 3 |
FAM221B | LINC00327 | 0.612949 | 3 | 0 | 3 |
FAM221B | CLDN16 | 0.610917 | 3 | 0 | 3 |
FAM221B | KIF25-AS1 | 0.591686 | 3 | 0 | 3 |
FAM221B | TMEM190 | 0.566877 | 3 | 0 | 3 |
FAM221B | MIR124-2HG | 0.562347 | 3 | 0 | 3 |
FAM221B | SYN1 | 0.547566 | 4 | 0 | 3 |
FAM221B | HHIP | 0.545288 | 4 | 0 | 4 |
FAM221B | RTP5 | 0.544878 | 5 | 0 | 3 |
FAM221B | CRYBB3 | 0.531737 | 4 | 0 | 3 |
FAM221B | LINC00527 | 0.529022 | 3 | 0 | 3 |
FAM221B | IRGC | 0.517842 | 4 | 0 | 3 |
For details and further investigation, click here