| Full name: zinc finger protein 517 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 340385 | HGNC ID: HGNC:27984 | Ensembl Gene: ENSG00000197363 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF517:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF517 | 340385 | 241112_at | -0.0015 | 0.9965 | |
| GSE26886 | ZNF517 | 340385 | 241112_at | 0.2537 | 0.0297 | |
| GSE45670 | ZNF517 | 340385 | 241112_at | -0.0515 | 0.5798 | |
| GSE53622 | ZNF517 | 340385 | 68484 | 0.1839 | 0.0045 | |
| GSE53624 | ZNF517 | 340385 | 68484 | 0.4225 | 0.0000 | |
| GSE63941 | ZNF517 | 340385 | 241112_at | 0.2132 | 0.1735 | |
| GSE77861 | ZNF517 | 340385 | 241112_at | -0.0345 | 0.7627 | |
| SRP007169 | ZNF517 | 340385 | RNAseq | -0.7703 | 0.3243 | |
| SRP064894 | ZNF517 | 340385 | RNAseq | 0.6816 | 0.0095 | |
| SRP133303 | ZNF517 | 340385 | RNAseq | -0.2323 | 0.1570 | |
| SRP159526 | ZNF517 | 340385 | RNAseq | 0.4518 | 0.2267 | |
| SRP193095 | ZNF517 | 340385 | RNAseq | 0.2731 | 0.0388 | |
| SRP219564 | ZNF517 | 340385 | RNAseq | 0.5087 | 0.3831 | |
| TCGA | ZNF517 | 340385 | RNAseq | -0.0135 | 0.8659 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF517 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF517:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF517 | 340385 | 18 | 1 | 11 | |
| GSE20123 | ZNF517 | 340385 | 18 | 1 | 11 | |
| GSE43470 | ZNF517 | 340385 | 16 | 2 | 25 | |
| GSE46452 | ZNF517 | 340385 | 28 | 0 | 31 | |
| GSE47630 | ZNF517 | 340385 | 25 | 1 | 14 | |
| GSE54993 | ZNF517 | 340385 | 0 | 25 | 45 | |
| GSE54994 | ZNF517 | 340385 | 39 | 1 | 13 | |
| GSE60625 | ZNF517 | 340385 | 3 | 4 | 4 | |
| GSE74703 | ZNF517 | 340385 | 14 | 1 | 21 | |
| GSE74704 | ZNF517 | 340385 | 11 | 0 | 9 | |
| TCGA | ZNF517 | 340385 | 63 | 2 | 31 |
Total number of gains: 235; Total number of losses: 38; Total Number of normals: 215.
Somatic mutations of ZNF517:
Generating mutation plots.
Highly correlated genes for ZNF517:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF517 | KCNK16 | 0.706755 | 3 | 0 | 3 |
| ZNF517 | SLC6A3 | 0.704688 | 4 | 0 | 4 |
| ZNF517 | ADRA1A | 0.703827 | 3 | 0 | 3 |
| ZNF517 | SIGLEC11 | 0.699855 | 5 | 0 | 4 |
| ZNF517 | CHTF18 | 0.68762 | 3 | 0 | 3 |
| ZNF517 | TMEM235 | 0.675818 | 3 | 0 | 3 |
| ZNF517 | GDF11 | 0.671616 | 5 | 0 | 5 |
| ZNF517 | GRIK4 | 0.671603 | 3 | 0 | 3 |
| ZNF517 | MPL | 0.669243 | 5 | 0 | 4 |
| ZNF517 | OR2H1 | 0.666681 | 4 | 0 | 4 |
| ZNF517 | FAM221B | 0.66213 | 3 | 0 | 3 |
| ZNF517 | FAM222A-AS1 | 0.661908 | 4 | 0 | 4 |
| ZNF517 | ATP8A2 | 0.655627 | 3 | 0 | 3 |
| ZNF517 | MIR146A | 0.654752 | 3 | 0 | 3 |
| ZNF517 | GPR182 | 0.654521 | 4 | 0 | 3 |
| ZNF517 | RNF151 | 0.652929 | 3 | 0 | 3 |
| ZNF517 | TSPAN11 | 0.649138 | 3 | 0 | 3 |
| ZNF517 | ZMYND10 | 0.647891 | 3 | 0 | 3 |
| ZNF517 | LINC00626 | 0.646805 | 3 | 0 | 3 |
| ZNF517 | POM121L12 | 0.646685 | 3 | 0 | 3 |
For details and further investigation, click here
