| Full name: immunity related GTPase cinema | Alias Symbol: Iigp5|CINEMA | ||
| Type: protein-coding gene | Cytoband: 19q13.31 | ||
| Entrez ID: 56269 | HGNC ID: HGNC:28835 | Ensembl Gene: ENSG00000124449 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of IRGC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IRGC | 56269 | 214392_at | -0.0269 | 0.9319 | |
| GSE20347 | IRGC | 56269 | 214392_at | 0.0016 | 0.9841 | |
| GSE23400 | IRGC | 56269 | 214392_at | -0.1111 | 0.0003 | |
| GSE26886 | IRGC | 56269 | 214392_at | -0.0253 | 0.8351 | |
| GSE29001 | IRGC | 56269 | 214392_at | -0.0501 | 0.6941 | |
| GSE38129 | IRGC | 56269 | 214392_at | -0.0377 | 0.4742 | |
| GSE45670 | IRGC | 56269 | 214392_at | -0.0560 | 0.5994 | |
| GSE53622 | IRGC | 56269 | 44903 | -0.1080 | 0.4513 | |
| GSE53624 | IRGC | 56269 | 44903 | 0.2629 | 0.0062 | |
| GSE63941 | IRGC | 56269 | 214392_at | 0.0704 | 0.7364 | |
| GSE77861 | IRGC | 56269 | 214392_at | -0.1588 | 0.1165 | |
| TCGA | IRGC | 56269 | RNAseq | 0.8014 | 0.5526 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IRGC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IRGC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IRGC | 56269 | 6 | 5 | 19 | |
| GSE20123 | IRGC | 56269 | 5 | 4 | 21 | |
| GSE43470 | IRGC | 56269 | 4 | 11 | 28 | |
| GSE46452 | IRGC | 56269 | 45 | 1 | 13 | |
| GSE47630 | IRGC | 56269 | 8 | 6 | 26 | |
| GSE54993 | IRGC | 56269 | 17 | 4 | 49 | |
| GSE54994 | IRGC | 56269 | 6 | 12 | 35 | |
| GSE60625 | IRGC | 56269 | 9 | 0 | 2 | |
| GSE74703 | IRGC | 56269 | 4 | 7 | 25 | |
| GSE74704 | IRGC | 56269 | 4 | 2 | 14 | |
| TCGA | IRGC | 56269 | 14 | 16 | 66 |
Total number of gains: 122; Total number of losses: 68; Total Number of normals: 298.
Somatic mutations of IRGC:
Generating mutation plots.
Highly correlated genes for IRGC:
Showing top 20/205 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IRGC | LINC00165 | 0.667646 | 3 | 0 | 3 |
| IRGC | FSTL4 | 0.660306 | 3 | 0 | 3 |
| IRGC | CYP2A6 | 0.65523 | 4 | 0 | 3 |
| IRGC | GSG1 | 0.651748 | 3 | 0 | 3 |
| IRGC | LINC01267 | 0.65166 | 3 | 0 | 3 |
| IRGC | BRSK2 | 0.651468 | 3 | 0 | 3 |
| IRGC | UNC79 | 0.64654 | 4 | 0 | 3 |
| IRGC | GPR82 | 0.629492 | 3 | 0 | 3 |
| IRGC | TNFAIP8L2 | 0.626705 | 3 | 0 | 3 |
| IRGC | NCR3 | 0.618219 | 4 | 0 | 3 |
| IRGC | LYL1 | 0.615399 | 3 | 0 | 3 |
| IRGC | XCR1 | 0.610641 | 4 | 0 | 3 |
| IRGC | KCNJ13 | 0.60174 | 3 | 0 | 3 |
| IRGC | CD160 | 0.597132 | 4 | 0 | 3 |
| IRGC | ZNF280A | 0.595682 | 3 | 0 | 3 |
| IRGC | FGF6 | 0.595335 | 6 | 0 | 3 |
| IRGC | SHC3 | 0.594819 | 3 | 0 | 3 |
| IRGC | PF4 | 0.592673 | 5 | 0 | 3 |
| IRGC | TSSK2 | 0.591526 | 6 | 0 | 5 |
| IRGC | OMP | 0.591256 | 4 | 0 | 3 |
For details and further investigation, click here
