| Full name: transmembrane protein 190 | Alias Symbol: MDAC1 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 147744 | HGNC ID: HGNC:29632 | Ensembl Gene: ENSG00000160472 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM190:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM190 | 147744 | 1552594_at | -0.2115 | 0.4030 | |
| GSE26886 | TMEM190 | 147744 | 1552594_at | 0.0260 | 0.8919 | |
| GSE45670 | TMEM190 | 147744 | 1552594_at | 0.0782 | 0.5457 | |
| GSE63941 | TMEM190 | 147744 | 1552594_at | -0.0386 | 0.8693 | |
| GSE77861 | TMEM190 | 147744 | 1552594_at | -0.0538 | 0.7049 | |
| GSE97050 | TMEM190 | 147744 | A_23_P107775 | 0.0951 | 0.6594 | |
| TCGA | TMEM190 | 147744 | RNAseq | 0.9539 | 0.2142 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM190 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TMEM190:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM190 | 147744 | 3 | 4 | 23 | |
| GSE20123 | TMEM190 | 147744 | 3 | 3 | 24 | |
| GSE43470 | TMEM190 | 147744 | 3 | 11 | 29 | |
| GSE46452 | TMEM190 | 147744 | 45 | 1 | 13 | |
| GSE47630 | TMEM190 | 147744 | 8 | 6 | 26 | |
| GSE54993 | TMEM190 | 147744 | 17 | 4 | 49 | |
| GSE54994 | TMEM190 | 147744 | 4 | 13 | 36 | |
| GSE60625 | TMEM190 | 147744 | 9 | 0 | 2 | |
| GSE74703 | TMEM190 | 147744 | 3 | 7 | 26 | |
| GSE74704 | TMEM190 | 147744 | 3 | 1 | 16 | |
| TCGA | TMEM190 | 147744 | 20 | 14 | 62 |
Total number of gains: 118; Total number of losses: 64; Total Number of normals: 306.
Somatic mutations of TMEM190:
Generating mutation plots.
Highly correlated genes for TMEM190:
Showing top 20/88 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM190 | GH2 | 0.714389 | 3 | 0 | 3 |
| TMEM190 | MICALL2 | 0.712016 | 3 | 0 | 3 |
| TMEM190 | MRAP | 0.708343 | 3 | 0 | 3 |
| TMEM190 | SNAI1 | 0.696008 | 3 | 0 | 3 |
| TMEM190 | HGFAC | 0.690281 | 3 | 0 | 3 |
| TMEM190 | CYP17A1 | 0.678561 | 3 | 0 | 3 |
| TMEM190 | PRB1 | 0.66695 | 3 | 0 | 3 |
| TMEM190 | ASCL1 | 0.662011 | 3 | 0 | 3 |
| TMEM190 | ROBO4 | 0.661969 | 3 | 0 | 3 |
| TMEM190 | TNFRSF13C | 0.653608 | 3 | 0 | 3 |
| TMEM190 | CEACAM3 | 0.649325 | 3 | 0 | 3 |
| TMEM190 | SYN1 | 0.641353 | 3 | 0 | 3 |
| TMEM190 | SSPO | 0.640418 | 3 | 0 | 3 |
| TMEM190 | OR2H2 | 0.639172 | 3 | 0 | 3 |
| TMEM190 | MPL | 0.637561 | 3 | 0 | 3 |
| TMEM190 | C2CD4B | 0.63506 | 3 | 0 | 3 |
| TMEM190 | SLC5A2 | 0.632722 | 3 | 0 | 3 |
| TMEM190 | ARHGDIG | 0.628378 | 4 | 0 | 3 |
| TMEM190 | GATA6 | 0.62371 | 3 | 0 | 3 |
| TMEM190 | HRH2 | 0.621243 | 3 | 0 | 3 |
For details and further investigation, click here
