FAM81A

 

Full name: family with sequence similarity 81 member A Alias Symbol: MGC26690
Type: protein-coding gene Cytoband: 15q22.2
Entrez ID: 145773 HGNC ID: HGNC:28379 Ensembl Gene: ENSG00000157470 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of FAM81A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FAM81A 145773 227756_at -0.1593 0.5682
GSE26886 FAM81A 145773 227756_at 0.2470 0.0307
GSE63941 FAM81A 145773 227756_at 0.6753 0.1111
GSE77861 FAM81A 145773 241481_at -0.1134 0.3361
SRP133303 FAM81A 145773 RNAseq 0.9179 0.0030
SRP159526 FAM81A 145773 RNAseq -0.2227 0.7299
SRP219564 FAM81A 145773 RNAseq 1.0239 0.1341
TCGA FAM81A 145773 RNAseq 0.0818 0.7420

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by FAM81A expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of FAM81A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FAM81A 145773 6 4 20
GSE20123 FAM81A 145773 6 3 21
GSE43470 FAM81A 145773 4 4 35
GSE46452 FAM81A 145773 3 7 49
GSE47630 FAM81A 145773 8 10 22
GSE54993 FAM81A 145773 5 6 59
GSE54994 FAM81A 145773 6 8 39
GSE60625 FAM81A 145773 4 0 7
GSE74703 FAM81A 145773 4 3 29
GSE74704 FAM81A 145773 2 3 15
TCGA FAM81A 145773 10 16 70

Total number of gains: 58; Total number of losses: 64; Total Number of normals: 366.  

 

Somatic mutations of FAM81A:

 

Generating mutation plots.

 

Highly correlated genes for FAM81A:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FAM81AEFNA20.697235303
FAM81AVSX10.685443303
FAM81AKCNK170.677102303
FAM81APRORY0.608569303
FAM81AADAMTS100.603495303
FAM81ACRYBA20.591415303
FAM81ACCDC1540.577136403
FAM81ANDOR10.571618303
FAM81AFAM131C0.535347403

For details and further investigation, click here