| Full name: visual system homeobox 1 | Alias Symbol: PPD|PPCD1 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 30813 | HGNC ID: HGNC:12723 | Ensembl Gene: ENSG00000100987 | OMIM ID: 605020 |
| Drug and gene relationship at DGIdb | |||
Expression of VSX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VSX1 | 30813 | 221124_s_at | -0.0700 | 0.8591 | |
| GSE20347 | VSX1 | 30813 | 221124_s_at | -0.0417 | 0.6183 | |
| GSE23400 | VSX1 | 30813 | 221124_s_at | -0.0922 | 0.0007 | |
| GSE26886 | VSX1 | 30813 | 221124_s_at | 0.4410 | 0.0123 | |
| GSE29001 | VSX1 | 30813 | 221124_s_at | -0.0908 | 0.3612 | |
| GSE38129 | VSX1 | 30813 | 221124_s_at | -0.0783 | 0.4180 | |
| GSE45670 | VSX1 | 30813 | 221124_s_at | -0.0076 | 0.9497 | |
| GSE53622 | VSX1 | 30813 | 5515 | -0.2321 | 0.0000 | |
| GSE53624 | VSX1 | 30813 | 5515 | -0.0371 | 0.3962 | |
| GSE63941 | VSX1 | 30813 | 221124_s_at | 0.0753 | 0.6392 | |
| GSE77861 | VSX1 | 30813 | 224074_at | -0.1615 | 0.1524 | |
| GSE97050 | VSX1 | 30813 | A_33_P3342295 | -0.0584 | 0.8034 | |
| SRP133303 | VSX1 | 30813 | RNAseq | 0.4473 | 0.0507 | |
| TCGA | VSX1 | 30813 | RNAseq | -1.4648 | 0.1149 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by VSX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VSX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VSX1 | 30813 | 12 | 2 | 16 | |
| GSE20123 | VSX1 | 30813 | 12 | 2 | 16 | |
| GSE43470 | VSX1 | 30813 | 11 | 1 | 31 | |
| GSE46452 | VSX1 | 30813 | 27 | 1 | 31 | |
| GSE47630 | VSX1 | 30813 | 17 | 4 | 19 | |
| GSE54993 | VSX1 | 30813 | 0 | 17 | 53 | |
| GSE54994 | VSX1 | 30813 | 27 | 1 | 25 | |
| GSE60625 | VSX1 | 30813 | 0 | 0 | 11 | |
| GSE74703 | VSX1 | 30813 | 10 | 1 | 25 | |
| GSE74704 | VSX1 | 30813 | 7 | 1 | 12 | |
| TCGA | VSX1 | 30813 | 44 | 9 | 43 |
Total number of gains: 167; Total number of losses: 39; Total Number of normals: 282.
Somatic mutations of VSX1:
Generating mutation plots.
Highly correlated genes for VSX1:
Showing top 20/673 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VSX1 | CCDC85A | 0.751045 | 3 | 0 | 3 |
| VSX1 | HYDIN | 0.707121 | 3 | 0 | 3 |
| VSX1 | NSMF | 0.69193 | 3 | 0 | 3 |
| VSX1 | CACNA1H | 0.688417 | 3 | 0 | 3 |
| VSX1 | FAM81A | 0.685443 | 3 | 0 | 3 |
| VSX1 | MROH9 | 0.663628 | 4 | 0 | 3 |
| VSX1 | ZNF460 | 0.659284 | 4 | 0 | 4 |
| VSX1 | NEUROG1 | 0.65563 | 5 | 0 | 5 |
| VSX1 | TBC1D21 | 0.648537 | 4 | 0 | 4 |
| VSX1 | STXBP6 | 0.648341 | 3 | 0 | 3 |
| VSX1 | UCN3 | 0.647333 | 3 | 0 | 3 |
| VSX1 | TMEM88B | 0.64053 | 3 | 0 | 3 |
| VSX1 | QPCTL | 0.639234 | 5 | 0 | 5 |
| VSX1 | ARVCF | 0.639186 | 5 | 0 | 3 |
| VSX1 | C2CD4B | 0.635618 | 3 | 0 | 3 |
| VSX1 | SARDH | 0.63402 | 5 | 0 | 4 |
| VSX1 | RPS6KA2-AS1 | 0.630472 | 4 | 0 | 3 |
| VSX1 | CEMP1 | 0.630052 | 6 | 0 | 5 |
| VSX1 | ZNF821 | 0.629346 | 4 | 0 | 4 |
| VSX1 | LINC01348 | 0.628194 | 4 | 0 | 3 |
For details and further investigation, click here
