| Full name: crystallin beta A2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 1412 | HGNC ID: HGNC:2395 | Ensembl Gene: ENSG00000163499 | OMIM ID: 600836 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CRYBA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRYBA2 | 1412 | 220136_s_at | -0.2735 | 0.2830 | |
| GSE20347 | CRYBA2 | 1412 | 220136_s_at | -0.0707 | 0.2544 | |
| GSE23400 | CRYBA2 | 1412 | 220136_s_at | -0.1155 | 0.0004 | |
| GSE26886 | CRYBA2 | 1412 | 220136_s_at | 0.2676 | 0.0982 | |
| GSE29001 | CRYBA2 | 1412 | 220136_s_at | -0.0414 | 0.8237 | |
| GSE38129 | CRYBA2 | 1412 | 220136_s_at | -0.1368 | 0.0508 | |
| GSE45670 | CRYBA2 | 1412 | 220136_s_at | 0.1845 | 0.1162 | |
| GSE53622 | CRYBA2 | 1412 | 124123 | -0.2139 | 0.0986 | |
| GSE53624 | CRYBA2 | 1412 | 124123 | -0.5102 | 0.0000 | |
| GSE63941 | CRYBA2 | 1412 | 220136_s_at | 0.2929 | 0.3142 | |
| GSE77861 | CRYBA2 | 1412 | 220136_s_at | -0.0872 | 0.4435 | |
| GSE97050 | CRYBA2 | 1412 | A_33_P3314231 | -0.0329 | 0.8918 | |
| TCGA | CRYBA2 | 1412 | RNAseq | -0.8736 | 0.2539 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRYBA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRYBA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRYBA2 | 1412 | 1 | 14 | 15 | |
| GSE20123 | CRYBA2 | 1412 | 1 | 13 | 16 | |
| GSE43470 | CRYBA2 | 1412 | 1 | 7 | 35 | |
| GSE46452 | CRYBA2 | 1412 | 0 | 5 | 54 | |
| GSE47630 | CRYBA2 | 1412 | 4 | 5 | 31 | |
| GSE54993 | CRYBA2 | 1412 | 1 | 2 | 67 | |
| GSE54994 | CRYBA2 | 1412 | 7 | 10 | 36 | |
| GSE60625 | CRYBA2 | 1412 | 0 | 3 | 8 | |
| GSE74703 | CRYBA2 | 1412 | 1 | 5 | 30 | |
| GSE74704 | CRYBA2 | 1412 | 1 | 7 | 12 | |
| TCGA | CRYBA2 | 1412 | 11 | 27 | 58 |
Total number of gains: 28; Total number of losses: 98; Total Number of normals: 362.
Somatic mutations of CRYBA2:
Generating mutation plots.
Highly correlated genes for CRYBA2:
Showing top 20/130 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRYBA2 | IL34 | 0.741334 | 3 | 0 | 3 |
| CRYBA2 | COL26A1 | 0.722876 | 3 | 0 | 3 |
| CRYBA2 | RASGEF1C | 0.689058 | 5 | 0 | 4 |
| CRYBA2 | BHLHE40 | 0.68508 | 3 | 0 | 3 |
| CRYBA2 | NDUFA4L2 | 0.664132 | 3 | 0 | 3 |
| CRYBA2 | TMEM151B | 0.655034 | 4 | 0 | 4 |
| CRYBA2 | C3orf22 | 0.651177 | 3 | 0 | 3 |
| CRYBA2 | PHF21B | 0.651135 | 4 | 0 | 3 |
| CRYBA2 | ADAM30 | 0.638547 | 3 | 0 | 3 |
| CRYBA2 | TRIM15 | 0.632397 | 5 | 0 | 5 |
| CRYBA2 | PEX11G | 0.630217 | 3 | 0 | 3 |
| CRYBA2 | ALX3 | 0.617251 | 5 | 0 | 4 |
| CRYBA2 | ZP1 | 0.616345 | 3 | 0 | 3 |
| CRYBA2 | VWA5B1 | 0.616203 | 4 | 0 | 3 |
| CRYBA2 | CCDC125 | 0.615821 | 4 | 0 | 3 |
| CRYBA2 | FAM99B | 0.610254 | 3 | 0 | 3 |
| CRYBA2 | MGAT5B | 0.609147 | 5 | 0 | 4 |
| CRYBA2 | ARFIP2 | 0.608687 | 3 | 0 | 3 |
| CRYBA2 | LINC01191 | 0.604527 | 3 | 0 | 3 |
| CRYBA2 | RASL10B | 0.6016 | 4 | 0 | 3 |
For details and further investigation, click here
