KLHL32

 

Full name: kelch like family member 32 Alias Symbol: 
Type: protein-coding gene Cytoband: 6q16.1
Entrez ID: 114792 HGNC ID: HGNC:21221 Ensembl Gene: ENSG00000186231 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of KLHL32:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KLHL32 114792 1553765_a_at 0.0375 0.8843
GSE26886 KLHL32 114792 1553765_a_at 0.1500 0.0361
GSE45670 KLHL32 114792 1553765_a_at 0.0199 0.7641
GSE53622 KLHL32 114792 33363 -0.3542 0.0563
GSE53624 KLHL32 114792 80435 -0.3145 0.0099
GSE63941 KLHL32 114792 1553765_a_at 0.0817 0.4932
GSE77861 KLHL32 114792 1553765_a_at 0.0359 0.6282
SRP133303 KLHL32 114792 RNAseq -0.3394 0.3431
TCGA KLHL32 114792 RNAseq -2.1268 0.0000

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by KLHL32 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KLHL32:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KLHL32 114792 1 3 26
GSE20123 KLHL32 114792 1 2 27
GSE43470 KLHL32 114792 3 2 38
GSE46452 KLHL32 114792 2 11 46
GSE47630 KLHL32 114792 8 6 26
GSE54993 KLHL32 114792 3 2 65
GSE54994 KLHL32 114792 8 8 37
GSE60625 KLHL32 114792 0 1 10
GSE74703 KLHL32 114792 2 2 32
GSE74704 KLHL32 114792 0 0 20
TCGA KLHL32 114792 4 25 67

Total number of gains: 32; Total number of losses: 62; Total Number of normals: 394.  

 

Somatic mutations of KLHL32:

 

Generating mutation plots.

 

Highly correlated genes for KLHL32:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KLHL32CPB20.630924303
KLHL32ZNF4920.618652303
KLHL32NTHL10.604525303
KLHL32CHAF1B0.570723303
KLHL32RPS6KL10.564977403
KLHL32LSM40.557175303
KLHL32INPP5B0.543812403

For details and further investigation, click here