| Full name: ribosomal protein S6 kinase like 1 | Alias Symbol: MGC11287|RSKL2 | ||
| Type: protein-coding gene | Cytoband: 14q24.2 | ||
| Entrez ID: 83694 | HGNC ID: HGNC:20222 | Ensembl Gene: ENSG00000198208 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RPS6KL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS6KL1 | 83694 | 223534_s_at | -0.1900 | 0.7526 | |
| GSE26886 | RPS6KL1 | 83694 | 223534_s_at | 0.3113 | 0.0542 | |
| GSE45670 | RPS6KL1 | 83694 | 223534_s_at | -0.1767 | 0.1031 | |
| GSE53622 | RPS6KL1 | 83694 | 38648 | -0.0075 | 0.9267 | |
| GSE53624 | RPS6KL1 | 83694 | 38648 | 0.0338 | 0.7238 | |
| GSE63941 | RPS6KL1 | 83694 | 223534_s_at | 0.1297 | 0.6663 | |
| GSE77861 | RPS6KL1 | 83694 | 223534_s_at | -0.1134 | 0.3871 | |
| GSE97050 | RPS6KL1 | 83694 | A_24_P219108 | -0.1881 | 0.4614 | |
| SRP007169 | RPS6KL1 | 83694 | RNAseq | 0.0850 | 0.9048 | |
| SRP064894 | RPS6KL1 | 83694 | RNAseq | -0.2426 | 0.3699 | |
| SRP133303 | RPS6KL1 | 83694 | RNAseq | -0.0312 | 0.7758 | |
| SRP159526 | RPS6KL1 | 83694 | RNAseq | 0.1178 | 0.7451 | |
| SRP193095 | RPS6KL1 | 83694 | RNAseq | 0.2849 | 0.0397 | |
| SRP219564 | RPS6KL1 | 83694 | RNAseq | -0.8941 | 0.1753 | |
| TCGA | RPS6KL1 | 83694 | RNAseq | -0.0380 | 0.8810 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPS6KL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS6KL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS6KL1 | 83694 | 8 | 3 | 19 | |
| GSE20123 | RPS6KL1 | 83694 | 8 | 3 | 19 | |
| GSE43470 | RPS6KL1 | 83694 | 8 | 3 | 32 | |
| GSE46452 | RPS6KL1 | 83694 | 16 | 3 | 40 | |
| GSE47630 | RPS6KL1 | 83694 | 11 | 8 | 21 | |
| GSE54993 | RPS6KL1 | 83694 | 3 | 8 | 59 | |
| GSE54994 | RPS6KL1 | 83694 | 19 | 4 | 30 | |
| GSE60625 | RPS6KL1 | 83694 | 0 | 2 | 9 | |
| GSE74703 | RPS6KL1 | 83694 | 7 | 3 | 26 | |
| GSE74704 | RPS6KL1 | 83694 | 3 | 3 | 14 | |
| TCGA | RPS6KL1 | 83694 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of RPS6KL1:
Generating mutation plots.
Highly correlated genes for RPS6KL1:
Showing top 20/135 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS6KL1 | GRIN1 | 0.721465 | 3 | 0 | 3 |
| RPS6KL1 | NKAIN4 | 0.72112 | 3 | 0 | 3 |
| RPS6KL1 | NPEPL1 | 0.709691 | 3 | 0 | 3 |
| RPS6KL1 | KBTBD12 | 0.709431 | 3 | 0 | 3 |
| RPS6KL1 | ITGB1BP2 | 0.697023 | 3 | 0 | 3 |
| RPS6KL1 | NPAS3 | 0.690867 | 3 | 0 | 3 |
| RPS6KL1 | PHGR1 | 0.684742 | 3 | 0 | 3 |
| RPS6KL1 | LRCH4 | 0.672418 | 4 | 0 | 4 |
| RPS6KL1 | PVALB | 0.658053 | 3 | 0 | 3 |
| RPS6KL1 | CPAMD8 | 0.652797 | 3 | 0 | 3 |
| RPS6KL1 | GUCY2C | 0.647965 | 3 | 0 | 3 |
| RPS6KL1 | DNAH6 | 0.645256 | 3 | 0 | 3 |
| RPS6KL1 | ENDOG | 0.644705 | 3 | 0 | 3 |
| RPS6KL1 | INSC | 0.639849 | 4 | 0 | 4 |
| RPS6KL1 | FOXO4 | 0.639564 | 4 | 0 | 3 |
| RPS6KL1 | NRXN1 | 0.63877 | 3 | 0 | 3 |
| RPS6KL1 | NKX2-8 | 0.637247 | 5 | 0 | 4 |
| RPS6KL1 | FUT7 | 0.637105 | 3 | 0 | 3 |
| RPS6KL1 | TSSK3 | 0.63366 | 3 | 0 | 3 |
| RPS6KL1 | PPOX | 0.632661 | 3 | 0 | 3 |
For details and further investigation, click here
