| Full name: LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated | Alias Symbol: YER112W | ||
| Type: protein-coding gene | Cytoband: 19p13.1 | ||
| Entrez ID: 25804 | HGNC ID: HGNC:17259 | Ensembl Gene: | OMIM ID: 607284 |
| Drug and gene relationship at DGIdb | |||
Expression of LSM4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LSM4 | 25804 | 202737_s_at | 0.6379 | 0.2876 | |
| GSE20347 | LSM4 | 25804 | 202737_s_at | 0.7800 | 0.0000 | |
| GSE23400 | LSM4 | 25804 | 202737_s_at | 0.9135 | 0.0000 | |
| GSE26886 | LSM4 | 25804 | 202737_s_at | 0.8524 | 0.0000 | |
| GSE29001 | LSM4 | 25804 | 202737_s_at | 0.6668 | 0.0610 | |
| GSE38129 | LSM4 | 25804 | 202737_s_at | 0.9101 | 0.0000 | |
| GSE45670 | LSM4 | 25804 | 202737_s_at | 0.6542 | 0.0001 | |
| GSE63941 | LSM4 | 25804 | 202736_s_at | 1.8605 | 0.0001 | |
| GSE77861 | LSM4 | 25804 | 202737_s_at | 0.5011 | 0.0414 | |
| GSE97050 | LSM4 | 25804 | A_24_P224776 | 0.3332 | 0.3172 | |
| SRP007169 | LSM4 | 25804 | RNAseq | 0.2106 | 0.6134 | |
| SRP008496 | LSM4 | 25804 | RNAseq | 0.2699 | 0.3857 | |
| SRP064894 | LSM4 | 25804 | RNAseq | 0.9705 | 0.0064 | |
| SRP133303 | LSM4 | 25804 | RNAseq | 0.6720 | 0.0041 | |
| SRP159526 | LSM4 | 25804 | RNAseq | 0.7725 | 0.0018 | |
| SRP193095 | LSM4 | 25804 | RNAseq | 0.2477 | 0.0793 | |
| SRP219564 | LSM4 | 25804 | RNAseq | 0.9208 | 0.0211 | |
| TCGA | LSM4 | 25804 | RNAseq | 0.2449 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LSM4 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of LSM4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LSM4 | 25804 | 4 | 4 | 22 | |
| GSE20123 | LSM4 | 25804 | 3 | 2 | 25 | |
| GSE43470 | LSM4 | 25804 | 2 | 6 | 35 | |
| GSE46452 | LSM4 | 25804 | 47 | 1 | 11 | |
| GSE47630 | LSM4 | 25804 | 4 | 8 | 28 | |
| GSE54993 | LSM4 | 25804 | 15 | 4 | 51 | |
| GSE54994 | LSM4 | 25804 | 6 | 13 | 34 | |
| GSE60625 | LSM4 | 25804 | 9 | 0 | 2 | |
| GSE74703 | LSM4 | 25804 | 2 | 4 | 30 | |
| GSE74704 | LSM4 | 25804 | 0 | 2 | 18 | |
| TCGA | LSM4 | 25804 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 54; Total Number of normals: 326.
Somatic mutations of LSM4:
Generating mutation plots.
Highly correlated genes for LSM4:
Showing top 20/1978 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LSM4 | SPNS1 | 0.839017 | 3 | 0 | 3 |
| LSM4 | ZNF317 | 0.797424 | 4 | 0 | 4 |
| LSM4 | COMMD7 | 0.796474 | 3 | 0 | 3 |
| LSM4 | ZFPL1 | 0.794188 | 3 | 0 | 3 |
| LSM4 | LAMTOR4 | 0.793153 | 4 | 0 | 4 |
| LSM4 | DHRSX | 0.791804 | 3 | 0 | 3 |
| LSM4 | MCM7 | 0.790093 | 10 | 0 | 9 |
| LSM4 | DNMT1 | 0.790043 | 10 | 0 | 10 |
| LSM4 | HIBADH | 0.779333 | 3 | 0 | 3 |
| LSM4 | LMNB2 | 0.778267 | 10 | 0 | 10 |
| LSM4 | HES4 | 0.776368 | 3 | 0 | 3 |
| LSM4 | TMEM216 | 0.774112 | 4 | 0 | 4 |
| LSM4 | LSM7 | 0.772521 | 10 | 0 | 10 |
| LSM4 | STPG1 | 0.769327 | 3 | 0 | 3 |
| LSM4 | PLEKHH1 | 0.767302 | 3 | 0 | 3 |
| LSM4 | PPP1R35 | 0.766102 | 6 | 0 | 6 |
| LSM4 | EZH2 | 0.762973 | 8 | 0 | 8 |
| LSM4 | RNASEH2A | 0.762657 | 11 | 0 | 9 |
| LSM4 | NR2C2AP | 0.762367 | 7 | 0 | 6 |
| LSM4 | SIX4 | 0.762326 | 5 | 0 | 5 |
For details and further investigation, click here
