| Full name: chromatin assembly factor 1 subunit B | Alias Symbol: CAF1P60|CAF-1|CAF1|CAF1A|MPP7|MPHOSPH7 | ||
| Type: protein-coding gene | Cytoband: 21q22.12-q22.13 | ||
| Entrez ID: 8208 | HGNC ID: HGNC:1911 | Ensembl Gene: ENSG00000159259 | OMIM ID: 601245 |
| Drug and gene relationship at DGIdb | |||
Expression of CHAF1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHAF1B | 8208 | 204775_at | 0.4809 | 0.1440 | |
| GSE20347 | CHAF1B | 8208 | 204775_at | 0.3197 | 0.0046 | |
| GSE23400 | CHAF1B | 8208 | 204775_at | 0.1472 | 0.0017 | |
| GSE26886 | CHAF1B | 8208 | 204775_at | 0.2424 | 0.1736 | |
| GSE29001 | CHAF1B | 8208 | 204775_at | 0.5178 | 0.0158 | |
| GSE38129 | CHAF1B | 8208 | 204775_at | 0.4845 | 0.0000 | |
| GSE45670 | CHAF1B | 8208 | 204775_at | 0.2251 | 0.0275 | |
| GSE53622 | CHAF1B | 8208 | 79341 | 0.6910 | 0.0000 | |
| GSE53624 | CHAF1B | 8208 | 79341 | 1.1914 | 0.0000 | |
| GSE63941 | CHAF1B | 8208 | 204775_at | 1.2515 | 0.0101 | |
| GSE77861 | CHAF1B | 8208 | 204775_at | 0.1782 | 0.3719 | |
| GSE97050 | CHAF1B | 8208 | A_23_P57306 | 0.5354 | 0.1673 | |
| SRP007169 | CHAF1B | 8208 | RNAseq | 0.5229 | 0.2535 | |
| SRP008496 | CHAF1B | 8208 | RNAseq | 0.9366 | 0.0122 | |
| SRP064894 | CHAF1B | 8208 | RNAseq | 0.9923 | 0.0003 | |
| SRP133303 | CHAF1B | 8208 | RNAseq | 0.4660 | 0.0048 | |
| SRP159526 | CHAF1B | 8208 | RNAseq | 1.0798 | 0.0004 | |
| SRP193095 | CHAF1B | 8208 | RNAseq | 0.5139 | 0.0000 | |
| SRP219564 | CHAF1B | 8208 | RNAseq | 0.8440 | 0.0539 | |
| TCGA | CHAF1B | 8208 | RNAseq | 0.8152 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CHAF1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CHAF1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHAF1B | 8208 | 2 | 8 | 20 | |
| GSE20123 | CHAF1B | 8208 | 2 | 9 | 19 | |
| GSE43470 | CHAF1B | 8208 | 1 | 11 | 31 | |
| GSE46452 | CHAF1B | 8208 | 1 | 21 | 37 | |
| GSE47630 | CHAF1B | 8208 | 6 | 17 | 17 | |
| GSE54993 | CHAF1B | 8208 | 8 | 1 | 61 | |
| GSE54994 | CHAF1B | 8208 | 2 | 9 | 42 | |
| GSE60625 | CHAF1B | 8208 | 0 | 0 | 11 | |
| GSE74703 | CHAF1B | 8208 | 1 | 8 | 27 | |
| GSE74704 | CHAF1B | 8208 | 1 | 5 | 14 | |
| TCGA | CHAF1B | 8208 | 9 | 39 | 48 |
Total number of gains: 33; Total number of losses: 128; Total Number of normals: 327.
Somatic mutations of CHAF1B:
Generating mutation plots.
Highly correlated genes for CHAF1B:
Showing top 20/1392 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHAF1B | RHBDD2 | 0.766485 | 4 | 0 | 4 |
| CHAF1B | SYNGR3 | 0.762315 | 3 | 0 | 3 |
| CHAF1B | MMS22L | 0.761133 | 3 | 0 | 3 |
| CHAF1B | LRRC34 | 0.755915 | 3 | 0 | 3 |
| CHAF1B | SPSB2 | 0.75324 | 3 | 0 | 3 |
| CHAF1B | NOP58 | 0.750398 | 3 | 0 | 3 |
| CHAF1B | LSM10 | 0.745429 | 3 | 0 | 3 |
| CHAF1B | ESCO2 | 0.742625 | 6 | 0 | 5 |
| CHAF1B | ATXN7L3B | 0.733449 | 3 | 0 | 3 |
| CHAF1B | EBNA1BP2 | 0.73174 | 3 | 0 | 3 |
| CHAF1B | SCNM1 | 0.72994 | 3 | 0 | 3 |
| CHAF1B | ZNF707 | 0.728967 | 3 | 0 | 3 |
| CHAF1B | LIN9 | 0.728655 | 5 | 0 | 5 |
| CHAF1B | MTHFD1L | 0.722041 | 3 | 0 | 3 |
| CHAF1B | DKC1 | 0.720249 | 3 | 0 | 3 |
| CHAF1B | PTCD1 | 0.718934 | 3 | 0 | 3 |
| CHAF1B | BORA | 0.717926 | 8 | 0 | 8 |
| CHAF1B | PYCR2 | 0.714653 | 3 | 0 | 3 |
| CHAF1B | CDKN2C | 0.71404 | 3 | 0 | 3 |
| CHAF1B | TRMU | 0.709481 | 3 | 0 | 3 |
For details and further investigation, click here
