| Full name: inositol polyphosphate-5-phosphatase B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p34.3 | ||
| Entrez ID: 3633 | HGNC ID: HGNC:6077 | Ensembl Gene: ENSG00000204084 | OMIM ID: 147264 |
| Drug and gene relationship at DGIdb | |||
Expression of INPP5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | INPP5B | 3633 | 213804_at | 0.0847 | 0.8715 | |
| GSE20347 | INPP5B | 3633 | 213804_at | -0.0886 | 0.3974 | |
| GSE23400 | INPP5B | 3633 | 213804_at | -0.1206 | 0.0085 | |
| GSE26886 | INPP5B | 3633 | 213804_at | 0.9020 | 0.0000 | |
| GSE29001 | INPP5B | 3633 | 213804_at | 0.1841 | 0.4412 | |
| GSE38129 | INPP5B | 3633 | 213804_at | -0.1785 | 0.0764 | |
| GSE45670 | INPP5B | 3633 | 213804_at | -0.1135 | 0.4410 | |
| GSE53622 | INPP5B | 3633 | 28419 | -0.0182 | 0.8036 | |
| GSE53624 | INPP5B | 3633 | 28419 | 0.1200 | 0.0849 | |
| GSE63941 | INPP5B | 3633 | 213643_s_at | 0.9011 | 0.0238 | |
| GSE77861 | INPP5B | 3633 | 213804_at | 0.1154 | 0.4869 | |
| GSE97050 | INPP5B | 3633 | A_23_P85640 | -0.0626 | 0.8339 | |
| SRP007169 | INPP5B | 3633 | RNAseq | 0.3452 | 0.5604 | |
| SRP008496 | INPP5B | 3633 | RNAseq | 0.1732 | 0.7260 | |
| SRP064894 | INPP5B | 3633 | RNAseq | 0.1579 | 0.3207 | |
| SRP133303 | INPP5B | 3633 | RNAseq | 0.0018 | 0.9865 | |
| SRP159526 | INPP5B | 3633 | RNAseq | -0.4400 | 0.0178 | |
| SRP193095 | INPP5B | 3633 | RNAseq | 0.1230 | 0.2615 | |
| SRP219564 | INPP5B | 3633 | RNAseq | -0.1241 | 0.7700 | |
| TCGA | INPP5B | 3633 | RNAseq | -0.1899 | 0.0022 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by INPP5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of INPP5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | INPP5B | 3633 | 2 | 4 | 24 | |
| GSE20123 | INPP5B | 3633 | 2 | 3 | 25 | |
| GSE43470 | INPP5B | 3633 | 7 | 3 | 33 | |
| GSE46452 | INPP5B | 3633 | 4 | 1 | 54 | |
| GSE47630 | INPP5B | 3633 | 8 | 3 | 29 | |
| GSE54993 | INPP5B | 3633 | 0 | 1 | 69 | |
| GSE54994 | INPP5B | 3633 | 12 | 2 | 39 | |
| GSE60625 | INPP5B | 3633 | 0 | 0 | 11 | |
| GSE74703 | INPP5B | 3633 | 6 | 2 | 28 | |
| GSE74704 | INPP5B | 3633 | 1 | 0 | 19 | |
| TCGA | INPP5B | 3633 | 12 | 17 | 67 |
Total number of gains: 54; Total number of losses: 36; Total Number of normals: 398.
Somatic mutations of INPP5B:
Generating mutation plots.
Highly correlated genes for INPP5B:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| INPP5B | OSBPL9 | 0.800768 | 3 | 0 | 3 |
| INPP5B | GRIN2D | 0.792065 | 3 | 0 | 3 |
| INPP5B | CENPBD1 | 0.78978 | 3 | 0 | 3 |
| INPP5B | TBPL1 | 0.787119 | 3 | 0 | 3 |
| INPP5B | SIN3A | 0.786059 | 3 | 0 | 3 |
| INPP5B | TXNDC16 | 0.784945 | 3 | 0 | 3 |
| INPP5B | CEP290 | 0.781802 | 3 | 0 | 3 |
| INPP5B | CEP89 | 0.773168 | 3 | 0 | 3 |
| INPP5B | NARF | 0.772012 | 3 | 0 | 3 |
| INPP5B | USP42 | 0.770566 | 3 | 0 | 3 |
| INPP5B | UBB | 0.770508 | 3 | 0 | 3 |
| INPP5B | GMEB2 | 0.769552 | 3 | 0 | 3 |
| INPP5B | ZNF628 | 0.767996 | 3 | 0 | 3 |
| INPP5B | BOD1 | 0.76685 | 3 | 0 | 3 |
| INPP5B | RSRC1 | 0.766101 | 4 | 0 | 3 |
| INPP5B | ZNF558 | 0.764147 | 3 | 0 | 3 |
| INPP5B | MED30 | 0.763947 | 3 | 0 | 3 |
| INPP5B | TRIM47 | 0.758992 | 3 | 0 | 3 |
| INPP5B | STRADA | 0.753144 | 3 | 0 | 3 |
| INPP5B | SOX13 | 0.751378 | 3 | 0 | 3 |
For details and further investigation, click here
