LCE2D

 

Full name: late cornified envelope 2D Alias Symbol: LEP12
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 353141 HGNC ID: HGNC:16518 Ensembl Gene: ENSG00000187223 OMIM ID: 612612
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of LCE2D:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 LCE2D 353141 175506 0.2736 0.0930
GSE53624 LCE2D 353141 175506 0.2226 0.2541
GSE97050 LCE2D 353141 A_33_P3236568 0.3530 0.5817
TCGA LCE2D 353141 RNAseq 2.5766 0.1256

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by LCE2D expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LCE2D:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LCE2D 353141 15 0 15
GSE20123 LCE2D 353141 15 0 15
GSE43470 LCE2D 353141 6 2 35
GSE46452 LCE2D 353141 3 1 55
GSE47630 LCE2D 353141 15 0 25
GSE54993 LCE2D 353141 0 4 66
GSE54994 LCE2D 353141 15 0 38
GSE60625 LCE2D 353141 0 0 11
GSE74703 LCE2D 353141 6 1 29
GSE74704 LCE2D 353141 7 0 13
TCGA LCE2D 353141 39 2 55

Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.  

 

Somatic mutations of LCE2D:

 

Generating mutation plots.

 

Highly correlated genes for LCE2D:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LCE2DLCE2B0.777007404
LCE2DLCE2A0.761073303
LCE2DLCE3B0.672598303
LCE2DLCE6A0.609582403
LCE2DLCE1B0.548855403
LCE2DGSDMA0.539534403

For details and further investigation, click here