LCE3B

 

Full name: late cornified envelope 3B Alias Symbol: LEP14
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 353143 HGNC ID: HGNC:29462 Ensembl Gene: ENSG00000187238 OMIM ID: 612614
Drug and gene relationship at DGIdb

 

Expression of LCE3B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 LCE3B 353143 19657 -0.0030 0.9890
GSE53624 LCE3B 353143 19657 -0.1862 0.1813
GSE97050 LCE3B 353143 A_23_P324538 0.3990 0.4649

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by LCE3B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LCE3B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LCE3B 353143 14 0 16
GSE20123 LCE3B 353143 14 0 16
GSE43470 LCE3B 353143 6 2 35
GSE46452 LCE3B 353143 3 1 55
GSE47630 LCE3B 353143 15 0 25
GSE54993 LCE3B 353143 0 4 66
GSE54994 LCE3B 353143 15 0 38
GSE60625 LCE3B 353143 0 0 11
GSE74703 LCE3B 353143 6 1 29
GSE74704 LCE3B 353143 7 0 13
TCGA LCE3B 353143 39 3 54

Total number of gains: 119; Total number of losses: 11; Total Number of normals: 358.  

 

Somatic mutations of LCE3B:

 

Generating mutation plots.

 

Highly correlated genes for LCE3B:

 

Showing all 11 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LCE3BLCE3D0.906494303
LCE3BLCE3C0.880181303
LCE3BLCE3E0.866092303
LCE3BLCE3A0.765673403
LCE3BLCE2D0.672598303
LCE3BGSDMA0.636983303
LCE3BALOX12B0.619828303
LCE3BSPRR1B0.559144303
LCE3BBPIFC0.557287303
LCE3BS100A120.538824303
LCE3BKRT160.529362303

For details and further investigation, click here