| Full name: late cornified envelope 1B | Alias Symbol: LEP2 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 353132 | HGNC ID: HGNC:16611 | Ensembl Gene: ENSG00000196734 | OMIM ID: 612604 |
| Drug and gene relationship at DGIdb | |||
Expression of LCE1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LCE1B | 353132 | 1560531_at | 0.2390 | 0.4574 | |
| GSE26886 | LCE1B | 353132 | 1560531_at | -0.0773 | 0.5952 | |
| GSE45670 | LCE1B | 353132 | 1560531_at | 0.2477 | 0.1620 | |
| GSE53622 | LCE1B | 353132 | 476 | 0.6343 | 0.0000 | |
| GSE53624 | LCE1B | 353132 | 476 | 0.1175 | 0.5401 | |
| GSE63941 | LCE1B | 353132 | 1560531_at | -0.0409 | 0.7549 | |
| GSE77861 | LCE1B | 353132 | 1560531_at | -0.0393 | 0.7715 | |
| GSE97050 | LCE1B | 353132 | A_33_P3356816 | -0.2155 | 0.5442 | |
| TCGA | LCE1B | 353132 | RNAseq | 3.4631 | 0.0002 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LCE1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCE1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCE1B | 353132 | 15 | 0 | 15 | |
| GSE20123 | LCE1B | 353132 | 15 | 0 | 15 | |
| GSE43470 | LCE1B | 353132 | 6 | 2 | 35 | |
| GSE46452 | LCE1B | 353132 | 3 | 1 | 55 | |
| GSE47630 | LCE1B | 353132 | 15 | 0 | 25 | |
| GSE54993 | LCE1B | 353132 | 0 | 4 | 66 | |
| GSE54994 | LCE1B | 353132 | 15 | 0 | 38 | |
| GSE60625 | LCE1B | 353132 | 0 | 0 | 11 | |
| GSE74703 | LCE1B | 353132 | 6 | 1 | 29 | |
| GSE74704 | LCE1B | 353132 | 7 | 0 | 13 | |
| TCGA | LCE1B | 353132 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of LCE1B:
Generating mutation plots.
Highly correlated genes for LCE1B:
Showing top 20/21 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCE1B | LINC01013 | 0.644298 | 3 | 0 | 3 |
| LCE1B | FBXL8 | 0.62075 | 3 | 0 | 3 |
| LCE1B | CACNA1G | 0.619027 | 3 | 0 | 3 |
| LCE1B | IL9R | 0.618267 | 3 | 0 | 3 |
| LCE1B | C14orf180 | 0.616041 | 3 | 0 | 3 |
| LCE1B | C1QTNF6 | 0.605026 | 4 | 0 | 3 |
| LCE1B | HS2ST1 | 0.58913 | 3 | 0 | 3 |
| LCE1B | KRT25 | 0.586374 | 3 | 0 | 3 |
| LCE1B | LCE2B | 0.580717 | 4 | 0 | 3 |
| LCE1B | LCE6A | 0.566306 | 4 | 0 | 3 |
| LCE1B | LCE2A | 0.563911 | 3 | 0 | 3 |
| LCE1B | PAX2 | 0.561645 | 4 | 0 | 3 |
| LCE1B | GHRHR | 0.555001 | 4 | 0 | 4 |
| LCE1B | LCE2D | 0.548855 | 4 | 0 | 3 |
| LCE1B | SMOC1 | 0.548778 | 3 | 0 | 3 |
| LCE1B | KIR2DL4 | 0.547759 | 4 | 0 | 3 |
| LCE1B | SLC5A4 | 0.546203 | 4 | 0 | 3 |
| LCE1B | MED19 | 0.531852 | 3 | 0 | 3 |
| LCE1B | SLC5A11 | 0.531448 | 4 | 0 | 3 |
| LCE1B | TEX13B | 0.518476 | 5 | 0 | 3 |
For details and further investigation, click here
