| Full name: gasdermin A | Alias Symbol: FLJ39120 | ||
| Type: protein-coding gene | Cytoband: 17q21.1 | ||
| Entrez ID: 284110 | HGNC ID: HGNC:13311 | Ensembl Gene: ENSG00000167914 | OMIM ID: 611218 |
| Drug and gene relationship at DGIdb | |||
Expression of GSDMA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | GSDMA | 284110 | 69426 | 0.2301 | 0.4051 | |
| GSE53624 | GSDMA | 284110 | 69426 | 0.1816 | 0.2351 | |
| GSE97050 | GSDMA | 284110 | A_23_P152605 | 0.4844 | 0.1584 | |
| SRP007169 | GSDMA | 284110 | RNAseq | -2.1292 | 0.0284 | |
| SRP064894 | GSDMA | 284110 | RNAseq | 0.5251 | 0.2558 | |
| SRP133303 | GSDMA | 284110 | RNAseq | -0.0981 | 0.7258 | |
| SRP159526 | GSDMA | 284110 | RNAseq | -0.2536 | 0.7811 | |
| SRP193095 | GSDMA | 284110 | RNAseq | -0.2733 | 0.3893 | |
| SRP219564 | GSDMA | 284110 | RNAseq | -1.1715 | 0.0423 | |
| TCGA | GSDMA | 284110 | RNAseq | 0.8289 | 0.0773 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GSDMA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GSDMA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GSDMA | 284110 | 9 | 1 | 20 | |
| GSE20123 | GSDMA | 284110 | 9 | 1 | 20 | |
| GSE43470 | GSDMA | 284110 | 1 | 2 | 40 | |
| GSE46452 | GSDMA | 284110 | 34 | 0 | 25 | |
| GSE47630 | GSDMA | 284110 | 8 | 1 | 31 | |
| GSE54993 | GSDMA | 284110 | 3 | 4 | 63 | |
| GSE54994 | GSDMA | 284110 | 9 | 5 | 39 | |
| GSE60625 | GSDMA | 284110 | 4 | 0 | 7 | |
| GSE74703 | GSDMA | 284110 | 1 | 1 | 34 | |
| GSE74704 | GSDMA | 284110 | 5 | 1 | 14 | |
| TCGA | GSDMA | 284110 | 23 | 8 | 65 |
Total number of gains: 106; Total number of losses: 24; Total Number of normals: 358.
Somatic mutations of GSDMA:
Generating mutation plots.
Highly correlated genes for GSDMA:
Showing all 19 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GSDMA | SPRR2G | 0.704185 | 4 | 0 | 4 |
| GSDMA | ALOXE3 | 0.657624 | 4 | 0 | 3 |
| GSDMA | LCE3C | 0.646626 | 3 | 0 | 3 |
| GSDMA | LCE3D | 0.645047 | 4 | 0 | 4 |
| GSDMA | LCE3B | 0.636983 | 3 | 0 | 3 |
| GSDMA | LCE3A | 0.621904 | 4 | 0 | 4 |
| GSDMA | LCE3E | 0.618056 | 4 | 0 | 4 |
| GSDMA | CDSN | 0.614919 | 4 | 0 | 4 |
| GSDMA | PGLYRP4 | 0.599169 | 3 | 0 | 3 |
| GSDMA | WFDC5 | 0.598412 | 4 | 0 | 3 |
| GSDMA | LYPD5 | 0.594466 | 3 | 0 | 3 |
| GSDMA | PLA2G4D | 0.593188 | 3 | 0 | 3 |
| GSDMA | KLK5 | 0.570639 | 3 | 0 | 3 |
| GSDMA | KLK4 | 0.569372 | 3 | 0 | 3 |
| GSDMA | ASPRV1 | 0.550034 | 4 | 0 | 3 |
| GSDMA | LCE2D | 0.539534 | 4 | 0 | 3 |
| GSDMA | WFDC12 | 0.533947 | 4 | 0 | 3 |
| GSDMA | S100A12 | 0.527617 | 4 | 0 | 3 |
| GSDMA | ABCA12 | 0.521093 | 4 | 0 | 3 |
For details and further investigation, click here
