LCE6A

 

Full name: late cornified envelope 6A Alias Symbol: 
Type: protein-coding gene Cytoband: 1q21.3
Entrez ID: 448835 HGNC ID: HGNC:31824 Ensembl Gene: ENSG00000235942 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of LCE6A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 LCE6A 448835 96989 0.5553 0.0000
GSE53624 LCE6A 448835 96989 0.6217 0.0000
GSE97050 LCE6A 448835 A_33_P3365072 0.0978 0.6286
TCGA LCE6A 448835 RNAseq 2.5944 0.0983

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by LCE6A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of LCE6A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LCE6A 448835 15 0 15
GSE20123 LCE6A 448835 15 0 15
GSE43470 LCE6A 448835 6 2 35
GSE46452 LCE6A 448835 3 1 55
GSE47630 LCE6A 448835 15 0 25
GSE54993 LCE6A 448835 0 4 66
GSE54994 LCE6A 448835 15 0 38
GSE60625 LCE6A 448835 0 0 11
GSE74703 LCE6A 448835 6 1 29
GSE74704 LCE6A 448835 7 0 13
TCGA LCE6A 448835 39 2 55

Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.  

 

Somatic mutations of LCE6A:

 

Generating mutation plots.

 

Highly correlated genes for LCE6A:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LCE6ALCE2A0.725247303
LCE6ALCE2B0.658521303
LCE6AZFHX20.626893303
LCE6ATRPV30.62159403
LCE6ALCE2D0.609582403
LCE6ALCE1B0.566306403

For details and further investigation, click here