| Full name: zinc finger homeobox 2 | Alias Symbol: KIAA1762|KIAA1056|ZFH-5 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 85446 | HGNC ID: HGNC:20152 | Ensembl Gene: ENSG00000136367 | OMIM ID: 617828 |
| Drug and gene relationship at DGIdb | |||
Expression of ZFHX2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZFHX2 | 85446 | 207699_at | 0.0460 | 0.8828 | |
| GSE20347 | ZFHX2 | 85446 | 207699_at | -0.0542 | 0.5077 | |
| GSE23400 | ZFHX2 | 85446 | 207699_at | -0.1179 | 0.0009 | |
| GSE26886 | ZFHX2 | 85446 | 207699_at | 0.0162 | 0.9303 | |
| GSE29001 | ZFHX2 | 85446 | 207699_at | -0.0296 | 0.8628 | |
| GSE38129 | ZFHX2 | 85446 | 207699_at | -0.1215 | 0.1677 | |
| GSE45670 | ZFHX2 | 85446 | 207699_at | 0.0988 | 0.3052 | |
| GSE53622 | ZFHX2 | 85446 | 102059 | 0.5800 | 0.0000 | |
| GSE53624 | ZFHX2 | 85446 | 102059 | 0.5452 | 0.0000 | |
| GSE63941 | ZFHX2 | 85446 | 207699_at | -0.0178 | 0.9321 | |
| GSE77861 | ZFHX2 | 85446 | 231946_at | -0.1170 | 0.2297 | |
| GSE97050 | ZFHX2 | 85446 | A_32_P226205 | -0.4086 | 0.2522 | |
| SRP133303 | ZFHX2 | 85446 | RNAseq | 0.0998 | 0.7580 | |
| SRP159526 | ZFHX2 | 85446 | RNAseq | 1.0586 | 0.0053 | |
| SRP219564 | ZFHX2 | 85446 | RNAseq | -0.2706 | 0.6899 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ZFHX2 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of ZFHX2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZFHX2 | 85446 | 8 | 1 | 21 | |
| GSE20123 | ZFHX2 | 85446 | 8 | 1 | 21 | |
| GSE43470 | ZFHX2 | 85446 | 7 | 2 | 34 | |
| GSE46452 | ZFHX2 | 85446 | 17 | 2 | 40 | |
| GSE47630 | ZFHX2 | 85446 | 11 | 10 | 19 | |
| GSE54993 | ZFHX2 | 85446 | 3 | 11 | 56 | |
| GSE54994 | ZFHX2 | 85446 | 18 | 5 | 30 | |
| GSE60625 | ZFHX2 | 85446 | 0 | 2 | 9 | |
| GSE74703 | ZFHX2 | 85446 | 6 | 2 | 28 | |
| GSE74704 | ZFHX2 | 85446 | 3 | 1 | 16 | |
| TCGA | ZFHX2 | 85446 | 27 | 14 | 55 |
Total number of gains: 108; Total number of losses: 51; Total Number of normals: 329.
Somatic mutations of ZFHX2:
Generating mutation plots.
Highly correlated genes for ZFHX2:
Showing top 20/1119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZFHX2 | HSF4 | 0.765023 | 3 | 0 | 3 |
| ZFHX2 | CELF4 | 0.761357 | 3 | 0 | 3 |
| ZFHX2 | FMR1NB | 0.746727 | 3 | 0 | 3 |
| ZFHX2 | OR10C1 | 0.746287 | 5 | 0 | 5 |
| ZFHX2 | NOS1 | 0.723498 | 4 | 0 | 4 |
| ZFHX2 | DHH | 0.72321 | 3 | 0 | 3 |
| ZFHX2 | IL20 | 0.713642 | 3 | 0 | 3 |
| ZFHX2 | HRC | 0.706392 | 4 | 0 | 4 |
| ZFHX2 | RLN3 | 0.706391 | 3 | 0 | 3 |
| ZFHX2 | PPP1R3F | 0.704933 | 4 | 0 | 4 |
| ZFHX2 | BRSK1 | 0.703179 | 3 | 0 | 3 |
| ZFHX2 | BPIFB4 | 0.70022 | 3 | 0 | 3 |
| ZFHX2 | ZNF81 | 0.700056 | 3 | 0 | 3 |
| ZFHX2 | LCN8 | 0.699692 | 3 | 0 | 3 |
| ZFHX2 | RAB3IL1 | 0.699421 | 6 | 0 | 5 |
| ZFHX2 | NT5C1A | 0.695128 | 3 | 0 | 3 |
| ZFHX2 | RAX2 | 0.694759 | 3 | 0 | 3 |
| ZFHX2 | IFNA4 | 0.692983 | 6 | 0 | 6 |
| ZFHX2 | BCL6B | 0.692507 | 3 | 0 | 3 |
| ZFHX2 | TCL6 | 0.690924 | 4 | 0 | 4 |
For details and further investigation, click here
