LINC00458

 

Full name: long intergenic non-protein coding RNA 458 Alias Symbol: LncRNA-ES3|ES3
Type: non-coding RNA Cytoband: 13q14.3
Entrez ID: 100507428 HGNC ID: HGNC:42807 Ensembl Gene: ENSG00000234787 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of LINC00458:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LINC00458 100507428 237275_at 0.0549 0.8036
GSE26886 LINC00458 100507428 1569287_at -0.0677 0.5804
GSE45670 LINC00458 100507428 1569287_at 0.0882 0.3117
GSE53622 LINC00458 100507428 81565 -0.1940 0.3801
GSE53624 LINC00458 100507428 81565 -0.3118 0.1379
GSE63941 LINC00458 100507428 237275_at -0.0166 0.9260
GSE77861 LINC00458 100507428 237275_at -0.1068 0.2104
SRP133303 LINC00458 100507428 RNAseq 0.5781 0.0631

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by LINC00458 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of LINC00458:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LINC00458 100507428 1 14 15
GSE20123 LINC00458 100507428 1 13 16
GSE43470 LINC00458 100507428 1 12 30
GSE46452 LINC00458 100507428 0 32 27
GSE47630 LINC00458 100507428 2 27 11
GSE54993 LINC00458 100507428 12 2 56
GSE54994 LINC00458 100507428 2 15 36
GSE60625 LINC00458 100507428 0 3 8
GSE74703 LINC00458 100507428 1 10 25
GSE74704 LINC00458 100507428 0 11 9
TCGA LINC00458 100507428 9 35 52

Total number of gains: 29; Total number of losses: 174; Total Number of normals: 285.  

 

Somatic mutations of LINC00458:

 

Generating mutation plots.

 

Highly correlated genes for LINC00458:

 

Showing all 8 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LINC00458GPR520.66017303
LINC00458LINC013560.613887403
LINC00458ZNF2080.580725303
LINC00458EFCAB50.569569303
LINC00458APBB20.542991303
LINC00458C12orf500.540583403
LINC00458CLEC4E0.534401403
LINC00458ADAMTSL50.508424503

For details and further investigation, click here