| Full name: G protein-coupled receptor 52 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q25.1 | ||
| Entrez ID: 9293 | HGNC ID: HGNC:4508 | Ensembl Gene: ENSG00000203737 | OMIM ID: 604106 |
| Drug and gene relationship at DGIdb | |||
Expression of GPR52:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GPR52 | 9293 | 221313_at | 0.0553 | 0.8659 | |
| GSE20347 | GPR52 | 9293 | 221313_at | 0.1350 | 0.1962 | |
| GSE23400 | GPR52 | 9293 | 221313_at | -0.0438 | 0.3616 | |
| GSE26886 | GPR52 | 9293 | 221313_at | 0.0149 | 0.9417 | |
| GSE29001 | GPR52 | 9293 | 221313_at | -0.2077 | 0.3176 | |
| GSE38129 | GPR52 | 9293 | 221313_at | -0.1087 | 0.4117 | |
| GSE45670 | GPR52 | 9293 | 221313_at | -0.0000 | 0.9998 | |
| GSE53622 | GPR52 | 9293 | 38477 | 0.4856 | 0.0000 | |
| GSE53624 | GPR52 | 9293 | 38477 | 0.1478 | 0.1687 | |
| GSE63941 | GPR52 | 9293 | 221313_at | 0.3242 | 0.0518 | |
| GSE77861 | GPR52 | 9293 | 221313_at | -0.0816 | 0.7125 | |
| GSE97050 | GPR52 | 9293 | A_23_P85534 | 0.4838 | 0.1449 | |
| SRP133303 | GPR52 | 9293 | RNAseq | 0.3001 | 0.1939 | |
| SRP193095 | GPR52 | 9293 | RNAseq | 0.0800 | 0.6286 | |
| TCGA | GPR52 | 9293 | RNAseq | 2.0828 | 0.0110 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GPR52 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GPR52:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GPR52 | 9293 | 12 | 0 | 18 | |
| GSE20123 | GPR52 | 9293 | 12 | 0 | 18 | |
| GSE43470 | GPR52 | 9293 | 7 | 2 | 34 | |
| GSE46452 | GPR52 | 9293 | 3 | 1 | 55 | |
| GSE47630 | GPR52 | 9293 | 14 | 0 | 26 | |
| GSE54993 | GPR52 | 9293 | 0 | 6 | 64 | |
| GSE54994 | GPR52 | 9293 | 15 | 0 | 38 | |
| GSE60625 | GPR52 | 9293 | 0 | 0 | 11 | |
| GSE74703 | GPR52 | 9293 | 7 | 2 | 27 | |
| GSE74704 | GPR52 | 9293 | 5 | 0 | 15 | |
| TCGA | GPR52 | 9293 | 41 | 4 | 51 |
Total number of gains: 116; Total number of losses: 15; Total Number of normals: 357.
Somatic mutations of GPR52:
Generating mutation plots.
Highly correlated genes for GPR52:
Showing top 20/705 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GPR52 | PHF7 | 0.767406 | 4 | 0 | 4 |
| GPR52 | TAS2R31 | 0.731618 | 3 | 0 | 3 |
| GPR52 | RAI1 | 0.725178 | 4 | 0 | 3 |
| GPR52 | IFNA4 | 0.718104 | 5 | 0 | 4 |
| GPR52 | EME2 | 0.717753 | 3 | 0 | 3 |
| GPR52 | KIR3DL3 | 0.711091 | 8 | 0 | 6 |
| GPR52 | TAS2R30 | 0.70782 | 3 | 0 | 3 |
| GPR52 | MCF2L | 0.702331 | 3 | 0 | 3 |
| GPR52 | ADAMTS13 | 0.699551 | 5 | 0 | 5 |
| GPR52 | GDPD5 | 0.698785 | 3 | 0 | 3 |
| GPR52 | BEND3 | 0.698352 | 3 | 0 | 3 |
| GPR52 | LIME1 | 0.692011 | 3 | 0 | 3 |
| GPR52 | USP29 | 0.690317 | 3 | 0 | 3 |
| GPR52 | LMF1 | 0.685825 | 4 | 0 | 4 |
| GPR52 | IL2RG | 0.685758 | 3 | 0 | 3 |
| GPR52 | REG3A | 0.684746 | 4 | 0 | 3 |
| GPR52 | TCP10 | 0.684021 | 5 | 0 | 5 |
| GPR52 | RAB3IL1 | 0.683466 | 8 | 0 | 6 |
| GPR52 | TDRD1 | 0.682212 | 5 | 0 | 5 |
| GPR52 | LINC00520 | 0.68085 | 3 | 0 | 3 |
For details and further investigation, click here
