| Full name: EF-hand calcium binding domain 5 | Alias Symbol: FLJ46247 | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 374786 | HGNC ID: HGNC:24801 | Ensembl Gene: ENSG00000176927 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EFCAB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFCAB5 | 374786 | 1558300_at | -0.0959 | 0.6907 | |
| GSE26886 | EFCAB5 | 374786 | 1558300_at | -0.1462 | 0.2324 | |
| GSE45670 | EFCAB5 | 374786 | 1558300_at | 0.0323 | 0.7387 | |
| GSE53622 | EFCAB5 | 374786 | 33611 | 0.2741 | 0.0292 | |
| GSE53624 | EFCAB5 | 374786 | 33611 | 0.0477 | 0.8145 | |
| GSE63941 | EFCAB5 | 374786 | 1558300_at | 0.1674 | 0.2919 | |
| GSE77861 | EFCAB5 | 374786 | 1558300_at | -0.0651 | 0.6108 | |
| GSE97050 | EFCAB5 | 374786 | A_33_P3237644 | 0.1947 | 0.5507 | |
| SRP133303 | EFCAB5 | 374786 | RNAseq | 0.0214 | 0.8764 | |
| SRP159526 | EFCAB5 | 374786 | RNAseq | -0.2844 | 0.5712 | |
| SRP193095 | EFCAB5 | 374786 | RNAseq | -0.0054 | 0.9717 | |
| SRP219564 | EFCAB5 | 374786 | RNAseq | -0.5323 | 0.3340 | |
| TCGA | EFCAB5 | 374786 | RNAseq | -0.4328 | 0.4338 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EFCAB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFCAB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFCAB5 | 374786 | 7 | 2 | 21 | |
| GSE20123 | EFCAB5 | 374786 | 8 | 2 | 20 | |
| GSE43470 | EFCAB5 | 374786 | 0 | 1 | 42 | |
| GSE46452 | EFCAB5 | 374786 | 33 | 1 | 25 | |
| GSE47630 | EFCAB5 | 374786 | 7 | 1 | 32 | |
| GSE54993 | EFCAB5 | 374786 | 2 | 3 | 65 | |
| GSE54994 | EFCAB5 | 374786 | 7 | 5 | 41 | |
| GSE60625 | EFCAB5 | 374786 | 4 | 0 | 7 | |
| GSE74703 | EFCAB5 | 374786 | 0 | 1 | 35 | |
| GSE74704 | EFCAB5 | 374786 | 5 | 2 | 13 | |
| TCGA | EFCAB5 | 374786 | 20 | 11 | 65 |
Total number of gains: 93; Total number of losses: 29; Total Number of normals: 366.
Somatic mutations of EFCAB5:
Generating mutation plots.
Highly correlated genes for EFCAB5:
Showing top 20/188 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFCAB5 | C20orf85 | 0.726878 | 3 | 0 | 3 |
| EFCAB5 | AGXT | 0.721222 | 3 | 0 | 3 |
| EFCAB5 | RBAKDN | 0.720327 | 3 | 0 | 3 |
| EFCAB5 | CREB3L3 | 0.71887 | 3 | 0 | 3 |
| EFCAB5 | ABHD1 | 0.70151 | 3 | 0 | 3 |
| EFCAB5 | VWA5B1 | 0.700011 | 4 | 0 | 3 |
| EFCAB5 | GSX1 | 0.674554 | 4 | 0 | 3 |
| EFCAB5 | LINC00858 | 0.673124 | 3 | 0 | 3 |
| EFCAB5 | ZNF596 | 0.669249 | 3 | 0 | 3 |
| EFCAB5 | CDH22 | 0.668604 | 5 | 0 | 5 |
| EFCAB5 | LINC01352 | 0.666683 | 3 | 0 | 3 |
| EFCAB5 | LINC00486 | 0.666152 | 4 | 0 | 4 |
| EFCAB5 | MROH7 | 0.662241 | 3 | 0 | 3 |
| EFCAB5 | PKNOX2 | 0.661259 | 3 | 0 | 3 |
| EFCAB5 | VHL | 0.652367 | 3 | 0 | 3 |
| EFCAB5 | IFNL2 | 0.651623 | 6 | 0 | 5 |
| EFCAB5 | TSPAN11 | 0.649582 | 4 | 0 | 4 |
| EFCAB5 | KLHL17 | 0.649508 | 4 | 0 | 3 |
| EFCAB5 | MIR4755 | 0.641881 | 3 | 0 | 3 |
| EFCAB5 | PAQR9 | 0.638559 | 3 | 0 | 3 |
For details and further investigation, click here
