| Full name: ADAMTS like 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 339366 | HGNC ID: HGNC:27912 | Ensembl Gene: ENSG00000185761 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADAMTSL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAMTSL5 | 339366 | 242200_at | -0.0027 | 0.9954 | |
| GSE26886 | ADAMTSL5 | 339366 | 242200_at | 0.1542 | 0.2557 | |
| GSE45670 | ADAMTSL5 | 339366 | 242200_at | 0.1186 | 0.2679 | |
| GSE53622 | ADAMTSL5 | 339366 | 69285 | -0.0268 | 0.6053 | |
| GSE53624 | ADAMTSL5 | 339366 | 69285 | 0.0318 | 0.6393 | |
| GSE63941 | ADAMTSL5 | 339366 | 242200_at | 0.3136 | 0.1227 | |
| GSE77861 | ADAMTSL5 | 339366 | 242200_at | -0.1542 | 0.2594 | |
| GSE97050 | ADAMTSL5 | 339366 | A_33_P3245489 | 0.0397 | 0.8570 | |
| SRP007169 | ADAMTSL5 | 339366 | RNAseq | -0.9431 | 0.0527 | |
| SRP008496 | ADAMTSL5 | 339366 | RNAseq | -1.3051 | 0.0003 | |
| SRP064894 | ADAMTSL5 | 339366 | RNAseq | -0.7818 | 0.0058 | |
| SRP133303 | ADAMTSL5 | 339366 | RNAseq | -0.5033 | 0.0208 | |
| SRP159526 | ADAMTSL5 | 339366 | RNAseq | -1.4970 | 0.0002 | |
| SRP193095 | ADAMTSL5 | 339366 | RNAseq | -0.6039 | 0.0007 | |
| SRP219564 | ADAMTSL5 | 339366 | RNAseq | -1.4501 | 0.0019 | |
| TCGA | ADAMTSL5 | 339366 | RNAseq | 0.3676 | 0.0471 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ADAMTSL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAMTSL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAMTSL5 | 339366 | 4 | 6 | 20 | |
| GSE20123 | ADAMTSL5 | 339366 | 4 | 5 | 21 | |
| GSE43470 | ADAMTSL5 | 339366 | 1 | 11 | 31 | |
| GSE46452 | ADAMTSL5 | 339366 | 47 | 1 | 11 | |
| GSE47630 | ADAMTSL5 | 339366 | 5 | 7 | 28 | |
| GSE54993 | ADAMTSL5 | 339366 | 16 | 3 | 51 | |
| GSE54994 | ADAMTSL5 | 339366 | 8 | 15 | 30 | |
| GSE60625 | ADAMTSL5 | 339366 | 9 | 0 | 2 | |
| GSE74703 | ADAMTSL5 | 339366 | 1 | 8 | 27 | |
| GSE74704 | ADAMTSL5 | 339366 | 3 | 3 | 14 | |
| TCGA | ADAMTSL5 | 339366 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 84; Total Number of normals: 300.
Somatic mutations of ADAMTSL5:
Generating mutation plots.
Highly correlated genes for ADAMTSL5:
Showing top 20/217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAMTSL5 | CRYBB2 | 0.794074 | 3 | 0 | 3 |
| ADAMTSL5 | RNF31 | 0.761736 | 3 | 0 | 3 |
| ADAMTSL5 | KRTAP19-2 | 0.742875 | 3 | 0 | 3 |
| ADAMTSL5 | ZNF546 | 0.73935 | 3 | 0 | 3 |
| ADAMTSL5 | ZNF594 | 0.73664 | 3 | 0 | 3 |
| ADAMTSL5 | HADHA | 0.73653 | 3 | 0 | 3 |
| ADAMTSL5 | ELFN1 | 0.73149 | 5 | 0 | 5 |
| ADAMTSL5 | ALDH1L2 | 0.723196 | 3 | 0 | 3 |
| ADAMTSL5 | ALKBH7 | 0.72157 | 3 | 0 | 3 |
| ADAMTSL5 | PI4K2A | 0.721484 | 3 | 0 | 3 |
| ADAMTSL5 | RBP2 | 0.715967 | 4 | 0 | 3 |
| ADAMTSL5 | ZNF878 | 0.715222 | 3 | 0 | 3 |
| ADAMTSL5 | GSTCD | 0.710486 | 3 | 0 | 3 |
| ADAMTSL5 | TRIM61 | 0.706185 | 3 | 0 | 3 |
| ADAMTSL5 | GPR37L1 | 0.705618 | 3 | 0 | 3 |
| ADAMTSL5 | APOBEC2 | 0.703947 | 3 | 0 | 3 |
| ADAMTSL5 | SNX17 | 0.703681 | 3 | 0 | 3 |
| ADAMTSL5 | TELO2 | 0.703077 | 3 | 0 | 3 |
| ADAMTSL5 | CDC42EP5 | 0.693508 | 4 | 0 | 3 |
| ADAMTSL5 | CLTB | 0.692303 | 3 | 0 | 3 |
For details and further investigation, click here
