REG4

 

Full name: regenerating family member 4 Alias Symbol: REG-IV|RELP|GISP
Type: protein-coding gene Cytoband: 1p12
Entrez ID: 83998 HGNC ID: HGNC:22977 Ensembl Gene: ENSG00000134193 OMIM ID: 609846

 

Expression of REG4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 REG4 83998 1554436_a_at 0.1141 0.5544
GSE26886 REG4 83998 223447_at 0.0301 0.8320
GSE45670 REG4 83998 223447_at 0.1622 0.0901
GSE53622 REG4 83998 7858 -0.8823 0.0001
GSE53624 REG4 83998 7858 -1.5482 0.0000
GSE63941 REG4 83998 223447_at -0.1902 0.3010
GSE77861 REG4 83998 238984_at -0.0935 0.3415
GSE97050 REG4 83998 A_23_P400310 -0.0768 0.7958
TCGA REG4 83998 RNAseq -2.3377 0.0068

Upregulated datasets: 0; Downregulated datasets: 2.  

 

Survival by REG4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of REG4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 REG4 83998 3 5 22
GSE20123 REG4 83998 4 5 21
GSE43470 REG4 83998 1 3 39
GSE46452 REG4 83998 2 1 56
GSE47630 REG4 83998 11 3 26
GSE54993 REG4 83998 0 2 68
GSE54994 REG4 83998 12 0 41
GSE60625 REG4 83998 0 0 11
GSE74703 REG4 83998 1 3 32
GSE74704 REG4 83998 2 3 15
TCGA REG4 83998 18 23 55

Total number of gains: 54; Total number of losses: 48; Total Number of normals: 386.  

 

Somatic mutations of REG4:

 

Generating mutation plots.

 

Highly correlated genes for REG4:

 

Showing all 8 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
REG4BCL6B0.654749303
REG4TAS2R30.626816303
REG4ZNF7320.612582303
REG4MEG30.562913403
REG4LGALS90.55311403
REG4BIN30.542416303
REG4GPR610.527846303
REG4CTAG20.52609403

For details and further investigation, click here