| Full name: BCL6B transcription repressor | Alias Symbol: ZBTB28|BAZF | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 255877 | HGNC ID: HGNC:1002 | Ensembl Gene: ENSG00000161940 | OMIM ID: 608992 |
| Drug and gene relationship at DGIdb | |||
Expression of BCL6B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BCL6B | 255877 | 228311_at | 0.4507 | 0.1283 | |
| GSE26886 | BCL6B | 255877 | 242148_at | 0.0747 | 0.5164 | |
| GSE45670 | BCL6B | 255877 | 228311_at | 0.1009 | 0.4731 | |
| GSE53622 | BCL6B | 255877 | 64224 | 0.0729 | 0.5981 | |
| GSE53624 | BCL6B | 255877 | 64224 | 0.3093 | 0.0050 | |
| GSE63941 | BCL6B | 255877 | 242148_at | 0.2246 | 0.0766 | |
| GSE77861 | BCL6B | 255877 | 243825_at | -0.1463 | 0.0954 | |
| GSE97050 | BCL6B | 255877 | A_23_P324813 | 0.2201 | 0.4423 | |
| SRP064894 | BCL6B | 255877 | RNAseq | 1.6314 | 0.0000 | |
| SRP133303 | BCL6B | 255877 | RNAseq | -0.1988 | 0.3975 | |
| SRP159526 | BCL6B | 255877 | RNAseq | 0.5371 | 0.1645 | |
| SRP193095 | BCL6B | 255877 | RNAseq | 1.0169 | 0.0000 | |
| SRP219564 | BCL6B | 255877 | RNAseq | 0.3887 | 0.4901 | |
| TCGA | BCL6B | 255877 | RNAseq | -0.3535 | 0.0064 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by BCL6B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BCL6B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BCL6B | 255877 | 4 | 2 | 24 | |
| GSE20123 | BCL6B | 255877 | 4 | 3 | 23 | |
| GSE43470 | BCL6B | 255877 | 1 | 4 | 38 | |
| GSE46452 | BCL6B | 255877 | 34 | 1 | 24 | |
| GSE47630 | BCL6B | 255877 | 7 | 1 | 32 | |
| GSE54993 | BCL6B | 255877 | 4 | 3 | 63 | |
| GSE54994 | BCL6B | 255877 | 5 | 8 | 40 | |
| GSE60625 | BCL6B | 255877 | 4 | 0 | 7 | |
| GSE74703 | BCL6B | 255877 | 1 | 2 | 33 | |
| GSE74704 | BCL6B | 255877 | 2 | 1 | 17 | |
| TCGA | BCL6B | 255877 | 18 | 20 | 58 |
Total number of gains: 84; Total number of losses: 45; Total Number of normals: 359.
Somatic mutations of BCL6B:
Generating mutation plots.
Highly correlated genes for BCL6B:
Showing top 20/97 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BCL6B | ADAMTS13 | 0.831779 | 3 | 0 | 3 |
| BCL6B | FBXO15 | 0.794973 | 3 | 0 | 3 |
| BCL6B | CPNE7 | 0.755798 | 3 | 0 | 3 |
| BCL6B | AVPR2 | 0.754208 | 3 | 0 | 3 |
| BCL6B | ASPHD1 | 0.74437 | 3 | 0 | 3 |
| BCL6B | TULP1 | 0.742265 | 3 | 0 | 3 |
| BCL6B | ACP5 | 0.737215 | 3 | 0 | 3 |
| BCL6B | GMIP | 0.731064 | 3 | 0 | 3 |
| BCL6B | SHANK1 | 0.723059 | 4 | 0 | 3 |
| BCL6B | CDH4 | 0.722778 | 3 | 0 | 3 |
| BCL6B | C9orf131 | 0.722093 | 3 | 0 | 3 |
| BCL6B | TMEM239 | 0.707721 | 3 | 0 | 3 |
| BCL6B | JSRP1 | 0.70295 | 3 | 0 | 3 |
| BCL6B | KIF17 | 0.700287 | 3 | 0 | 3 |
| BCL6B | SYNGAP1 | 0.700124 | 3 | 0 | 3 |
| BCL6B | HAMP | 0.697341 | 3 | 0 | 3 |
| BCL6B | ZFHX2 | 0.692507 | 3 | 0 | 3 |
| BCL6B | MC3R | 0.692282 | 3 | 0 | 3 |
| BCL6B | CRYAA | 0.687685 | 3 | 0 | 3 |
| BCL6B | HDAC8 | 0.686338 | 3 | 0 | 3 |
For details and further investigation, click here
