| Full name: galectin 9 | Alias Symbol: LGALS9A | ||
| Type: protein-coding gene | Cytoband: 17q11.2 | ||
| Entrez ID: 3965 | HGNC ID: HGNC:6570 | Ensembl Gene: ENSG00000168961 | OMIM ID: 601879 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of LGALS9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LGALS9 | 3965 | 203236_s_at | 0.1433 | 0.7768 | |
| GSE20347 | LGALS9 | 3965 | 203236_s_at | -0.2473 | 0.1137 | |
| GSE23400 | LGALS9 | 3965 | 203236_s_at | 0.0587 | 0.4717 | |
| GSE26886 | LGALS9 | 3965 | 203236_s_at | 0.0874 | 0.6931 | |
| GSE29001 | LGALS9 | 3965 | 203236_s_at | 0.0773 | 0.8231 | |
| GSE38129 | LGALS9 | 3965 | 203236_s_at | -0.0787 | 0.6033 | |
| GSE45670 | LGALS9 | 3965 | 203236_s_at | 0.0775 | 0.5238 | |
| GSE53622 | LGALS9 | 3965 | 51576 | -0.6999 | 0.0000 | |
| GSE53624 | LGALS9 | 3965 | 51576 | -0.8594 | 0.0000 | |
| GSE63941 | LGALS9 | 3965 | 203236_s_at | 0.5092 | 0.4935 | |
| GSE77861 | LGALS9 | 3965 | 203236_s_at | -0.3822 | 0.0659 | |
| GSE97050 | LGALS9 | 3965 | A_23_P116557 | -0.2608 | 0.8055 | |
| SRP007169 | LGALS9 | 3965 | RNAseq | 0.4147 | 0.5115 | |
| SRP008496 | LGALS9 | 3965 | RNAseq | 0.1194 | 0.7890 | |
| SRP064894 | LGALS9 | 3965 | RNAseq | 1.0193 | 0.0010 | |
| SRP133303 | LGALS9 | 3965 | RNAseq | 0.4472 | 0.0473 | |
| SRP159526 | LGALS9 | 3965 | RNAseq | -0.3021 | 0.5864 | |
| SRP193095 | LGALS9 | 3965 | RNAseq | -0.4221 | 0.1863 | |
| SRP219564 | LGALS9 | 3965 | RNAseq | 0.9474 | 0.0730 | |
| TCGA | LGALS9 | 3965 | RNAseq | -0.2836 | 0.0014 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LGALS9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LGALS9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LGALS9 | 3965 | 8 | 3 | 19 | |
| GSE20123 | LGALS9 | 3965 | 8 | 3 | 19 | |
| GSE43470 | LGALS9 | 3965 | 0 | 1 | 42 | |
| GSE46452 | LGALS9 | 3965 | 33 | 1 | 25 | |
| GSE47630 | LGALS9 | 3965 | 7 | 1 | 32 | |
| GSE54993 | LGALS9 | 3965 | 2 | 3 | 65 | |
| GSE54994 | LGALS9 | 3965 | 6 | 6 | 41 | |
| GSE60625 | LGALS9 | 3965 | 4 | 0 | 7 | |
| GSE74703 | LGALS9 | 3965 | 0 | 1 | 35 | |
| GSE74704 | LGALS9 | 3965 | 6 | 1 | 13 | |
| TCGA | LGALS9 | 3965 | 21 | 11 | 64 |
Total number of gains: 95; Total number of losses: 31; Total Number of normals: 362.
Somatic mutations of LGALS9:
Generating mutation plots.
Highly correlated genes for LGALS9:
Showing top 20/125 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LGALS9 | MSMB | 0.679874 | 3 | 0 | 3 |
| LGALS9 | TLE3 | 0.677651 | 3 | 0 | 3 |
| LGALS9 | AQP5 | 0.661308 | 4 | 0 | 4 |
| LGALS9 | FOLR1 | 0.649349 | 3 | 0 | 3 |
| LGALS9 | KCNJ13 | 0.639193 | 3 | 0 | 3 |
| LGALS9 | TNFSF13B | 0.636382 | 3 | 0 | 3 |
| LGALS9 | KCNJ4 | 0.633536 | 3 | 0 | 3 |
| LGALS9 | ERBB4 | 0.62612 | 4 | 0 | 3 |
| LGALS9 | KLHDC7B | 0.621016 | 4 | 0 | 4 |
| LGALS9 | SDK2 | 0.614548 | 3 | 0 | 3 |
| LGALS9 | NKX3-1 | 0.607551 | 3 | 0 | 3 |
| LGALS9 | ZNF831 | 0.60742 | 4 | 0 | 3 |
| LGALS9 | AZGP1 | 0.603576 | 4 | 0 | 3 |
| LGALS9 | IL21R | 0.601564 | 7 | 0 | 5 |
| LGALS9 | IL10RA | 0.600222 | 6 | 0 | 4 |
| LGALS9 | AMN | 0.594223 | 4 | 0 | 4 |
| LGALS9 | SLA | 0.586227 | 5 | 0 | 4 |
| LGALS9 | RTP3 | 0.585965 | 4 | 0 | 3 |
| LGALS9 | DCSTAMP | 0.580523 | 3 | 0 | 3 |
| LGALS9 | VWCE | 0.579646 | 4 | 0 | 4 |
For details and further investigation, click here
