| Full name: ring finger protein 224 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 643596 | HGNC ID: HGNC:41912 | Ensembl Gene: ENSG00000233198 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RNF224:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | RNF224 | 643596 | 159828 | -0.2357 | 0.0013 | |
| GSE53624 | RNF224 | 643596 | 159828 | -0.2836 | 0.0005 | |
| GSE97050 | RNF224 | 643596 | A_33_P3243558 | -0.1286 | 0.5727 | |
| SRP064894 | RNF224 | 643596 | RNAseq | -3.4811 | 0.0000 | |
| SRP133303 | RNF224 | 643596 | RNAseq | -4.2587 | 0.0000 | |
| SRP159526 | RNF224 | 643596 | RNAseq | -4.8376 | 0.0000 | |
| SRP219564 | RNF224 | 643596 | RNAseq | -3.2376 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RNF224 expression:
Note: Click image to view full size file.
Copy number change of RNF224:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RNF224 | 643596 | 5 | 7 | 18 | |
| GSE20123 | RNF224 | 643596 | 5 | 7 | 18 | |
| GSE43470 | RNF224 | 643596 | 3 | 7 | 33 | |
| GSE46452 | RNF224 | 643596 | 6 | 13 | 40 | |
| GSE47630 | RNF224 | 643596 | 6 | 15 | 19 | |
| GSE54993 | RNF224 | 643596 | 3 | 3 | 64 | |
| GSE54994 | RNF224 | 643596 | 12 | 8 | 33 | |
| GSE60625 | RNF224 | 643596 | 0 | 0 | 11 | |
| GSE74703 | RNF224 | 643596 | 3 | 5 | 28 | |
| GSE74704 | RNF224 | 643596 | 3 | 5 | 12 | |
| TCGA | RNF224 | 643596 | 29 | 23 | 44 |
Total number of gains: 75; Total number of losses: 93; Total Number of normals: 320.
Somatic mutations of RNF224:
Generating mutation plots.
Highly correlated genes for RNF224:
Showing all 8 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RNF224 | FOXP4 | 0.752325 | 3 | 0 | 3 |
| RNF224 | ZNF467 | 0.743655 | 3 | 0 | 3 |
| RNF224 | COG3 | 0.693373 | 3 | 0 | 3 |
| RNF224 | SPATA21 | 0.692571 | 3 | 0 | 3 |
| RNF224 | WWOX | 0.686753 | 3 | 0 | 3 |
| RNF224 | MYH7 | 0.68113 | 3 | 0 | 3 |
| RNF224 | EXD3 | 0.662018 | 3 | 0 | 3 |
| RNF224 | ADAD2 | 0.640031 | 3 | 0 | 3 |
For details and further investigation, click here

