| Full name: WW domain containing oxidoreductase | Alias Symbol: FOR|WOX1|SDR41C1 | ||
| Type: protein-coding gene | Cytoband: 16q23.1-q23.2 | ||
| Entrez ID: 51741 | HGNC ID: HGNC:12799 | Ensembl Gene: ENSG00000186153 | OMIM ID: 605131 |
| Drug and gene relationship at DGIdb | |||
Expression of WWOX:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WWOX | 51741 | 219077_s_at | -0.6739 | 0.0155 | |
| GSE20347 | WWOX | 51741 | 219077_s_at | -0.5625 | 0.0144 | |
| GSE23400 | WWOX | 51741 | 210695_s_at | -0.1077 | 0.0027 | |
| GSE26886 | WWOX | 51741 | 219077_s_at | -0.1335 | 0.7188 | |
| GSE29001 | WWOX | 51741 | 219077_s_at | -0.6798 | 0.0716 | |
| GSE38129 | WWOX | 51741 | 219077_s_at | -0.4348 | 0.0111 | |
| GSE45670 | WWOX | 51741 | 219077_s_at | -0.4550 | 0.0698 | |
| GSE53622 | WWOX | 51741 | 60464 | -0.2409 | 0.0076 | |
| GSE53624 | WWOX | 51741 | 60464 | -0.3307 | 0.0000 | |
| GSE63941 | WWOX | 51741 | 219077_s_at | -0.4116 | 0.7330 | |
| GSE77861 | WWOX | 51741 | 210695_s_at | -0.1425 | 0.2525 | |
| GSE97050 | WWOX | 51741 | A_33_P3305023 | 0.1962 | 0.4324 | |
| SRP007169 | WWOX | 51741 | RNAseq | -0.8069 | 0.0305 | |
| SRP008496 | WWOX | 51741 | RNAseq | -0.8126 | 0.0148 | |
| SRP064894 | WWOX | 51741 | RNAseq | -0.2842 | 0.1997 | |
| SRP133303 | WWOX | 51741 | RNAseq | -0.0035 | 0.9874 | |
| SRP159526 | WWOX | 51741 | RNAseq | 0.1675 | 0.6500 | |
| SRP193095 | WWOX | 51741 | RNAseq | 0.0017 | 0.9896 | |
| SRP219564 | WWOX | 51741 | RNAseq | 0.0531 | 0.8873 | |
| TCGA | WWOX | 51741 | RNAseq | -0.0410 | 0.6540 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WWOX expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WWOX:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WWOX | 51741 | 4 | 3 | 23 | |
| GSE20123 | WWOX | 51741 | 3 | 3 | 24 | |
| GSE43470 | WWOX | 51741 | 2 | 8 | 33 | |
| GSE46452 | WWOX | 51741 | 37 | 2 | 20 | |
| GSE47630 | WWOX | 51741 | 11 | 8 | 21 | |
| GSE54993 | WWOX | 51741 | 3 | 4 | 63 | |
| GSE54994 | WWOX | 51741 | 7 | 11 | 35 | |
| GSE60625 | WWOX | 51741 | 4 | 0 | 7 | |
| GSE74703 | WWOX | 51741 | 2 | 6 | 28 | |
| GSE74704 | WWOX | 51741 | 3 | 2 | 15 | |
| TCGA | WWOX | 51741 | 29 | 23 | 44 |
Total number of gains: 105; Total number of losses: 70; Total Number of normals: 313.
Somatic mutations of WWOX:
Generating mutation plots.
Highly correlated genes for WWOX:
Showing top 20/474 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WWOX | KIR3DL2 | 0.773806 | 3 | 0 | 3 |
| WWOX | KRTAP19-2 | 0.733352 | 3 | 0 | 3 |
| WWOX | ADAD2 | 0.728296 | 3 | 0 | 3 |
| WWOX | KRTAP21-2 | 0.7256 | 3 | 0 | 3 |
| WWOX | RNF14 | 0.724851 | 3 | 0 | 3 |
| WWOX | SCUBE2 | 0.713774 | 4 | 0 | 4 |
| WWOX | HOOK3 | 0.713574 | 3 | 0 | 3 |
| WWOX | LRFN5 | 0.705832 | 3 | 0 | 3 |
| WWOX | ZRANB1 | 0.704532 | 4 | 0 | 3 |
| WWOX | ARL2BP | 0.700227 | 3 | 0 | 3 |
| WWOX | ALG13 | 0.692258 | 3 | 0 | 3 |
| WWOX | ZNF608 | 0.691872 | 3 | 0 | 3 |
| WWOX | FBXL3 | 0.691534 | 5 | 0 | 4 |
| WWOX | RBPJL | 0.688229 | 4 | 0 | 3 |
| WWOX | SLTM | 0.688219 | 5 | 0 | 4 |
| WWOX | RNF224 | 0.686753 | 3 | 0 | 3 |
| WWOX | SFTPA2 | 0.685469 | 3 | 0 | 3 |
| WWOX | KAT5 | 0.683085 | 3 | 0 | 3 |
| WWOX | ERCC8 | 0.682986 | 3 | 0 | 3 |
| WWOX | ZNF33A | 0.681159 | 5 | 0 | 5 |
For details and further investigation, click here
