| Full name: exonuclease 3'-5' domain containing 3 | Alias Symbol: LOC54932|FLJ20433|mut-7 | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 54932 | HGNC ID: HGNC:26023 | Ensembl Gene: ENSG00000187609 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EXD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EXD3 | 54932 | 241363_at | -0.1866 | 0.6068 | |
| GSE20347 | EXD3 | 54932 | 220838_at | -0.1233 | 0.1271 | |
| GSE23400 | EXD3 | 54932 | 220838_at | -0.0318 | 0.4529 | |
| GSE26886 | EXD3 | 54932 | 220838_at | 0.1148 | 0.4682 | |
| GSE29001 | EXD3 | 54932 | 220838_at | 0.1676 | 0.3223 | |
| GSE38129 | EXD3 | 54932 | 220838_at | -0.0880 | 0.3375 | |
| GSE45670 | EXD3 | 54932 | 220838_at | 0.2155 | 0.0169 | |
| GSE53622 | EXD3 | 54932 | 54269 | -0.2199 | 0.0001 | |
| GSE53624 | EXD3 | 54932 | 54269 | -0.1724 | 0.0351 | |
| GSE63941 | EXD3 | 54932 | 241363_at | 0.5927 | 0.2083 | |
| GSE77861 | EXD3 | 54932 | 220838_at | -0.1804 | 0.2851 | |
| GSE97050 | EXD3 | 54932 | A_33_P3319261 | -0.3005 | 0.2495 | |
| SRP007169 | EXD3 | 54932 | RNAseq | -1.4420 | 0.0031 | |
| SRP008496 | EXD3 | 54932 | RNAseq | -0.9109 | 0.0075 | |
| SRP064894 | EXD3 | 54932 | RNAseq | 0.0557 | 0.8400 | |
| SRP133303 | EXD3 | 54932 | RNAseq | -0.6343 | 0.0005 | |
| SRP159526 | EXD3 | 54932 | RNAseq | -0.1117 | 0.6514 | |
| SRP193095 | EXD3 | 54932 | RNAseq | -0.3439 | 0.0604 | |
| SRP219564 | EXD3 | 54932 | RNAseq | -0.6623 | 0.1555 | |
| TCGA | EXD3 | 54932 | RNAseq | -0.1574 | 0.0588 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EXD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EXD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EXD3 | 54932 | 5 | 7 | 18 | |
| GSE20123 | EXD3 | 54932 | 5 | 7 | 18 | |
| GSE43470 | EXD3 | 54932 | 3 | 7 | 33 | |
| GSE46452 | EXD3 | 54932 | 6 | 13 | 40 | |
| GSE47630 | EXD3 | 54932 | 6 | 15 | 19 | |
| GSE54993 | EXD3 | 54932 | 3 | 3 | 64 | |
| GSE54994 | EXD3 | 54932 | 18 | 5 | 30 | |
| GSE60625 | EXD3 | 54932 | 0 | 0 | 11 | |
| GSE74703 | EXD3 | 54932 | 3 | 5 | 28 | |
| GSE74704 | EXD3 | 54932 | 3 | 5 | 12 | |
| TCGA | EXD3 | 54932 | 30 | 23 | 43 |
Total number of gains: 82; Total number of losses: 90; Total Number of normals: 316.
Somatic mutations of EXD3:
Generating mutation plots.
Highly correlated genes for EXD3:
Showing top 20/319 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EXD3 | ARL1 | 0.777766 | 3 | 0 | 3 |
| EXD3 | IL34 | 0.715514 | 3 | 0 | 3 |
| EXD3 | PPP2R1A | 0.704511 | 3 | 0 | 3 |
| EXD3 | ACTR1A | 0.699431 | 3 | 0 | 3 |
| EXD3 | LINC01432 | 0.69319 | 3 | 0 | 3 |
| EXD3 | KIR3DL2 | 0.690261 | 3 | 0 | 3 |
| EXD3 | TCAP | 0.688175 | 4 | 0 | 4 |
| EXD3 | OR7E24 | 0.686342 | 3 | 0 | 3 |
| EXD3 | UBL5 | 0.684316 | 3 | 0 | 3 |
| EXD3 | SPATA31E1 | 0.684071 | 3 | 0 | 3 |
| EXD3 | PCSK6 | 0.675067 | 5 | 0 | 4 |
| EXD3 | PPP1R1B | 0.674813 | 3 | 0 | 3 |
| EXD3 | ZNF584 | 0.673886 | 3 | 0 | 3 |
| EXD3 | SERHL2 | 0.671417 | 5 | 0 | 4 |
| EXD3 | HMCN2 | 0.671137 | 4 | 0 | 4 |
| EXD3 | SYN3 | 0.668565 | 5 | 0 | 5 |
| EXD3 | ADAD2 | 0.663843 | 6 | 0 | 6 |
| EXD3 | C19orf18 | 0.663737 | 3 | 0 | 3 |
| EXD3 | TSNARE1 | 0.663399 | 3 | 0 | 3 |
| EXD3 | RNF224 | 0.662018 | 3 | 0 | 3 |
For details and further investigation, click here
