| Full name: adenosine deaminase domain containing 2 | Alias Symbol: TENRL|FLJ00337 | ||
| Type: protein-coding gene | Cytoband: 16q24.1 | ||
| Entrez ID: 161931 | HGNC ID: HGNC:30714 | Ensembl Gene: ENSG00000140955 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ADAD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAD2 | 161931 | 236463_at | -0.0570 | 0.8752 | |
| GSE26886 | ADAD2 | 161931 | 236463_at | -0.0320 | 0.8269 | |
| GSE45670 | ADAD2 | 161931 | 236463_at | -0.0759 | 0.4568 | |
| GSE53622 | ADAD2 | 161931 | 124052 | -0.3173 | 0.0000 | |
| GSE53624 | ADAD2 | 161931 | 124052 | -0.4603 | 0.0000 | |
| GSE63941 | ADAD2 | 161931 | 236463_at | 0.2801 | 0.0284 | |
| GSE77861 | ADAD2 | 161931 | 236463_at | -0.0604 | 0.7592 | |
| GSE97050 | ADAD2 | 161931 | A_33_P3272402 | -0.1600 | 0.4946 | |
| SRP064894 | ADAD2 | 161931 | RNAseq | -1.3783 | 0.0020 | |
| SRP133303 | ADAD2 | 161931 | RNAseq | -1.6078 | 0.0000 | |
| SRP159526 | ADAD2 | 161931 | RNAseq | -1.2070 | 0.0298 | |
| SRP219564 | ADAD2 | 161931 | RNAseq | -1.6151 | 0.0478 | |
| TCGA | ADAD2 | 161931 | RNAseq | 0.8807 | 0.0360 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by ADAD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ADAD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAD2 | 161931 | 4 | 4 | 22 | |
| GSE20123 | ADAD2 | 161931 | 4 | 4 | 22 | |
| GSE43470 | ADAD2 | 161931 | 2 | 10 | 31 | |
| GSE46452 | ADAD2 | 161931 | 37 | 2 | 20 | |
| GSE47630 | ADAD2 | 161931 | 11 | 9 | 20 | |
| GSE54993 | ADAD2 | 161931 | 3 | 4 | 63 | |
| GSE54994 | ADAD2 | 161931 | 8 | 10 | 35 | |
| GSE60625 | ADAD2 | 161931 | 4 | 0 | 7 | |
| GSE74703 | ADAD2 | 161931 | 2 | 7 | 27 | |
| GSE74704 | ADAD2 | 161931 | 3 | 2 | 15 | |
| TCGA | ADAD2 | 161931 | 26 | 16 | 54 |
Total number of gains: 104; Total number of losses: 68; Total Number of normals: 316.
Somatic mutations of ADAD2:
Generating mutation plots.
Highly correlated genes for ADAD2:
Showing top 20/226 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAD2 | DNAAF2 | 0.825514 | 3 | 0 | 3 |
| ADAD2 | TMEM53 | 0.806292 | 5 | 0 | 5 |
| ADAD2 | ZBTB16 | 0.776267 | 3 | 0 | 3 |
| ADAD2 | ZBTB10 | 0.759597 | 3 | 0 | 3 |
| ADAD2 | TRIM39 | 0.745302 | 3 | 0 | 3 |
| ADAD2 | KRTAP19-2 | 0.739127 | 3 | 0 | 3 |
| ADAD2 | WWOX | 0.728296 | 3 | 0 | 3 |
| ADAD2 | SRP68 | 0.720518 | 3 | 0 | 3 |
| ADAD2 | PRPF38A | 0.720025 | 3 | 0 | 3 |
| ADAD2 | CDH24 | 0.716953 | 3 | 0 | 3 |
| ADAD2 | MYO9A | 0.716387 | 3 | 0 | 3 |
| ADAD2 | ATF7 | 0.713862 | 3 | 0 | 3 |
| ADAD2 | CDKN2D | 0.709428 | 3 | 0 | 3 |
| ADAD2 | RAB35 | 0.706624 | 3 | 0 | 3 |
| ADAD2 | ENTPD2 | 0.700732 | 4 | 0 | 3 |
| ADAD2 | PIK3CB | 0.699083 | 3 | 0 | 3 |
| ADAD2 | REEP2 | 0.694424 | 4 | 0 | 4 |
| ADAD2 | THAP4 | 0.693024 | 3 | 0 | 3 |
| ADAD2 | PPP1R11 | 0.691676 | 3 | 0 | 3 |
| ADAD2 | TCAP | 0.686668 | 3 | 0 | 3 |
For details and further investigation, click here
