SEL1L2

 

Full name: SEL1L2 adaptor subunit of ERAD E3 ligase Alias Symbol: DKFZp434C1826
Type: protein-coding gene Cytoband: 20p12.1
Entrez ID: 80343 HGNC ID: HGNC:15897 Ensembl Gene: ENSG00000101251 OMIM ID: 614289
Drug and gene relationship at DGIdb

 

Expression of SEL1L2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SEL1L2 80343 234018_s_at 0.0034 0.9906
GSE26886 SEL1L2 80343 234018_s_at 0.1550 0.1269
GSE45670 SEL1L2 80343 234018_s_at 0.0890 0.2499
GSE53622 SEL1L2 80343 5672 -0.1060 0.3398
GSE53624 SEL1L2 80343 5672 -0.1219 0.1952
GSE63941 SEL1L2 80343 234018_s_at 0.0428 0.7432
GSE77861 SEL1L2 80343 234018_s_at -0.1812 0.1094

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by SEL1L2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SEL1L2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SEL1L2 80343 10 1 19
GSE20123 SEL1L2 80343 10 1 19
GSE43470 SEL1L2 80343 11 1 31
GSE46452 SEL1L2 80343 26 1 32
GSE47630 SEL1L2 80343 18 4 18
GSE54993 SEL1L2 80343 0 15 55
GSE54994 SEL1L2 80343 25 1 27
GSE60625 SEL1L2 80343 0 0 11
GSE74703 SEL1L2 80343 8 1 27
GSE74704 SEL1L2 80343 4 1 15
TCGA SEL1L2 80343 43 10 43

Total number of gains: 155; Total number of losses: 36; Total Number of normals: 297.  

 

Somatic mutations of SEL1L2:

 

Generating mutation plots.

 

Highly correlated genes for SEL1L2:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SEL1L2IRAK20.65931303
SEL1L2C9orf570.57407303
SEL1L2MT1E0.554536303
SEL1L2AVPR20.544945403
SEL1L2GRM10.54056403
SEL1L2TP730.53458403

For details and further investigation, click here