| Full name: arginine vasopressin receptor 2 | Alias Symbol: V2R | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 554 | HGNC ID: HGNC:897 | Ensembl Gene: ENSG00000126895 | OMIM ID: 300538 |
| Drug and gene relationship at DGIdb | |||
AVPR2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04072 | Phospholipase D signaling pathway | |
| hsa04962 | Vasopressin-regulated water reabsorption |
Expression of AVPR2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AVPR2 | 554 | 208111_at | -0.0337 | 0.9065 | |
| GSE20347 | AVPR2 | 554 | 208111_at | -0.1783 | 0.0228 | |
| GSE23400 | AVPR2 | 554 | 208108_s_at | -0.1295 | 0.0000 | |
| GSE26886 | AVPR2 | 554 | 208111_at | 0.1666 | 0.3309 | |
| GSE29001 | AVPR2 | 554 | 208108_s_at | 0.0314 | 0.8502 | |
| GSE38129 | AVPR2 | 554 | 208111_at | -0.2936 | 0.0001 | |
| GSE45670 | AVPR2 | 554 | 208111_at | 0.0595 | 0.6234 | |
| GSE53622 | AVPR2 | 554 | 60530 | 0.0300 | 0.6893 | |
| GSE53624 | AVPR2 | 554 | 168670 | 0.0363 | 0.6161 | |
| GSE63941 | AVPR2 | 554 | 208111_at | 0.2334 | 0.2212 | |
| GSE77861 | AVPR2 | 554 | 208111_at | -0.2227 | 0.2046 | |
| GSE97050 | AVPR2 | 554 | A_23_P346800 | 0.0305 | 0.9029 | |
| SRP133303 | AVPR2 | 554 | RNAseq | -1.1852 | 0.0025 | |
| SRP159526 | AVPR2 | 554 | RNAseq | -0.4964 | 0.3557 | |
| TCGA | AVPR2 | 554 | RNAseq | -1.3163 | 0.0014 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by AVPR2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AVPR2:
No record found for this gene.
Somatic mutations of AVPR2:
Generating mutation plots.
Highly correlated genes for AVPR2:
Showing top 20/532 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AVPR2 | LINC00302 | 0.804546 | 3 | 0 | 3 |
| AVPR2 | PGC | 0.772291 | 3 | 0 | 3 |
| AVPR2 | B3GALT1 | 0.758336 | 3 | 0 | 3 |
| AVPR2 | BCL6B | 0.754208 | 3 | 0 | 3 |
| AVPR2 | PPP1R3F | 0.751611 | 4 | 0 | 3 |
| AVPR2 | EBF4 | 0.742593 | 3 | 0 | 3 |
| AVPR2 | NCAN | 0.739283 | 4 | 0 | 3 |
| AVPR2 | ORM1 | 0.735837 | 4 | 0 | 4 |
| AVPR2 | PSPN | 0.73049 | 4 | 0 | 4 |
| AVPR2 | C1QTNF6 | 0.730456 | 3 | 0 | 3 |
| AVPR2 | NRG2 | 0.721726 | 3 | 0 | 3 |
| AVPR2 | VCX2 | 0.716912 | 4 | 0 | 4 |
| AVPR2 | LRFN2 | 0.713484 | 3 | 0 | 3 |
| AVPR2 | VMO1 | 0.713088 | 3 | 0 | 3 |
| AVPR2 | F2RL3 | 0.705525 | 4 | 0 | 3 |
| AVPR2 | RASL10B | 0.703686 | 4 | 0 | 4 |
| AVPR2 | ADAMTS4 | 0.697208 | 3 | 0 | 3 |
| AVPR2 | LILRA3 | 0.694846 | 4 | 0 | 4 |
| AVPR2 | NTRK1 | 0.692959 | 4 | 0 | 3 |
| AVPR2 | DUSP15 | 0.691579 | 4 | 0 | 3 |
For details and further investigation, click here
