| Full name: SH3 domain containing ring finger 1 | Alias Symbol: POSH|RNF142|KIAA1494 | ||
| Type: protein-coding gene | Cytoband: 4q32.3-q33 | ||
| Entrez ID: 57630 | HGNC ID: HGNC:17650 | Ensembl Gene: ENSG00000154447 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SH3RF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SH3RF1 | 57630 | 225589_at | 0.0732 | 0.9200 | |
| GSE26886 | SH3RF1 | 57630 | 225589_at | 0.3751 | 0.1891 | |
| GSE45670 | SH3RF1 | 57630 | 225589_at | -0.3423 | 0.2039 | |
| GSE53622 | SH3RF1 | 57630 | 106321 | 0.0937 | 0.4836 | |
| GSE53624 | SH3RF1 | 57630 | 106321 | -0.0164 | 0.8553 | |
| GSE63941 | SH3RF1 | 57630 | 225589_at | -0.3556 | 0.5300 | |
| GSE77861 | SH3RF1 | 57630 | 225589_at | 0.0295 | 0.9243 | |
| GSE97050 | SH3RF1 | 57630 | A_24_P100551 | 0.2037 | 0.4169 | |
| SRP007169 | SH3RF1 | 57630 | RNAseq | -0.2167 | 0.6016 | |
| SRP008496 | SH3RF1 | 57630 | RNAseq | 0.0572 | 0.8248 | |
| SRP064894 | SH3RF1 | 57630 | RNAseq | -0.1123 | 0.6080 | |
| SRP133303 | SH3RF1 | 57630 | RNAseq | 0.4654 | 0.0362 | |
| SRP159526 | SH3RF1 | 57630 | RNAseq | 1.2286 | 0.0417 | |
| SRP193095 | SH3RF1 | 57630 | RNAseq | -0.4114 | 0.1462 | |
| SRP219564 | SH3RF1 | 57630 | RNAseq | -0.3788 | 0.4440 | |
| TCGA | SH3RF1 | 57630 | RNAseq | -0.3387 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SH3RF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SH3RF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SH3RF1 | 57630 | 2 | 11 | 17 | |
| GSE20123 | SH3RF1 | 57630 | 2 | 11 | 17 | |
| GSE43470 | SH3RF1 | 57630 | 0 | 13 | 30 | |
| GSE46452 | SH3RF1 | 57630 | 1 | 36 | 22 | |
| GSE47630 | SH3RF1 | 57630 | 0 | 22 | 18 | |
| GSE54993 | SH3RF1 | 57630 | 10 | 0 | 60 | |
| GSE54994 | SH3RF1 | 57630 | 1 | 13 | 39 | |
| GSE60625 | SH3RF1 | 57630 | 0 | 0 | 11 | |
| GSE74703 | SH3RF1 | 57630 | 0 | 11 | 25 | |
| GSE74704 | SH3RF1 | 57630 | 1 | 5 | 14 | |
| TCGA | SH3RF1 | 57630 | 12 | 33 | 51 |
Total number of gains: 29; Total number of losses: 155; Total Number of normals: 304.
Somatic mutations of SH3RF1:
Generating mutation plots.
Highly correlated genes for SH3RF1:
Showing all 7 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SH3RF1 | SMUG1 | 0.647485 | 3 | 0 | 3 |
| SH3RF1 | CDK17 | 0.560461 | 3 | 0 | 3 |
| SH3RF1 | CCDC89 | 0.542352 | 4 | 0 | 3 |
| SH3RF1 | ZNF227 | 0.541914 | 3 | 0 | 3 |
| SH3RF1 | ZFAND4 | 0.529963 | 4 | 0 | 3 |
| SH3RF1 | ZNF616 | 0.513541 | 4 | 0 | 3 |
| SH3RF1 | CHMP6 | 0.511137 | 3 | 0 | 3 |
For details and further investigation, click here
