ZNF227

 

Full name: zinc finger protein 227 Alias Symbol: 
Type: protein-coding gene Cytoband: 19q13.32
Entrez ID: 7770 HGNC ID: HGNC:13020 Ensembl Gene: ENSG00000131115 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ZNF227:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZNF227 7770 227689_at -0.0009 0.9989
GSE20347 ZNF227 7770 217403_s_at 0.2359 0.0356
GSE23400 ZNF227 7770 217403_s_at 0.2026 0.0017
GSE26886 ZNF227 7770 227689_at -0.1690 0.5718
GSE29001 ZNF227 7770 217403_s_at 0.0985 0.3768
GSE38129 ZNF227 7770 217403_s_at 0.3924 0.0019
GSE45670 ZNF227 7770 227689_at 0.0016 0.9936
GSE53622 ZNF227 7770 139594 0.2004 0.0706
GSE53624 ZNF227 7770 139594 0.3238 0.0089
GSE63941 ZNF227 7770 227689_at -0.3310 0.4152
GSE77861 ZNF227 7770 227689_at -0.0640 0.7272
GSE97050 ZNF227 7770 A_23_P371011 -0.0522 0.8116
SRP007169 ZNF227 7770 RNAseq 0.7148 0.0733
SRP008496 ZNF227 7770 RNAseq 0.8526 0.0180
SRP064894 ZNF227 7770 RNAseq 0.4333 0.0053
SRP133303 ZNF227 7770 RNAseq 0.2115 0.2516
SRP159526 ZNF227 7770 RNAseq 0.7226 0.0538
SRP193095 ZNF227 7770 RNAseq 0.0776 0.5007
SRP219564 ZNF227 7770 RNAseq 0.1087 0.7155
TCGA ZNF227 7770 RNAseq -0.1014 0.1346

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ZNF227 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ZNF227:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZNF227 7770 7 5 18
GSE20123 ZNF227 7770 6 4 20
GSE43470 ZNF227 7770 4 11 28
GSE46452 ZNF227 7770 45 1 13
GSE47630 ZNF227 7770 8 6 26
GSE54993 ZNF227 7770 17 4 49
GSE54994 ZNF227 7770 6 12 35
GSE60625 ZNF227 7770 9 0 2
GSE74703 ZNF227 7770 4 7 25
GSE74704 ZNF227 7770 5 2 13
TCGA ZNF227 7770 14 16 66

Total number of gains: 125; Total number of losses: 68; Total Number of normals: 295.  

 

Somatic mutations of ZNF227:

 

Generating mutation plots.

 

Highly correlated genes for ZNF227:

 

Showing top 20/682 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZNF227BRD80.820259303
ZNF227VRK30.808519303
ZNF227VAMP30.782783303
ZNF227DCP1B0.781235303
ZNF227FBXL140.781003303
ZNF227PAN30.770271303
ZNF227RBM8A0.763201303
ZNF227NAA300.760272404
ZNF227CRK0.75116303
ZNF227HEATR5A0.748612303
ZNF227ZNF33A0.748574303
ZNF227ZRANB20.744179303
ZNF227ATG140.72856404
ZNF227RPS90.728034303
ZNF227RWDD40.724306404
ZNF227ARID20.716593303
ZNF227UBL50.713504303
ZNF227MACROD20.712222303
ZNF227TRIM590.711904303
ZNF227RPL180.711133303

For details and further investigation, click here