| Full name: coiled-coil domain containing 89 | Alias Symbol: FLJ38159 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 220388 | HGNC ID: HGNC:26762 | Ensembl Gene: ENSG00000179071 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of CCDC89:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCDC89 | 220388 | 1553228_at | 0.0211 | 0.9522 | |
| GSE26886 | CCDC89 | 220388 | 1553228_at | 0.1513 | 0.2117 | |
| GSE45670 | CCDC89 | 220388 | 1553228_at | -0.0508 | 0.5354 | |
| GSE53622 | CCDC89 | 220388 | 118038 | -0.0307 | 0.7962 | |
| GSE53624 | CCDC89 | 220388 | 118038 | -0.0323 | 0.7915 | |
| GSE63941 | CCDC89 | 220388 | 1553228_at | -1.8584 | 0.0000 | |
| GSE77861 | CCDC89 | 220388 | 1553228_at | -0.0064 | 0.9325 | |
| GSE97050 | CCDC89 | 220388 | A_24_P192988 | -0.1506 | 0.4474 | |
| SRP133303 | CCDC89 | 220388 | RNAseq | 0.2855 | 0.2890 | |
| TCGA | CCDC89 | 220388 | RNAseq | -0.9787 | 0.0065 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CCDC89 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCDC89:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCDC89 | 220388 | 4 | 9 | 17 | |
| GSE20123 | CCDC89 | 220388 | 4 | 9 | 17 | |
| GSE43470 | CCDC89 | 220388 | 3 | 4 | 36 | |
| GSE46452 | CCDC89 | 220388 | 6 | 24 | 29 | |
| GSE47630 | CCDC89 | 220388 | 2 | 19 | 19 | |
| GSE54993 | CCDC89 | 220388 | 8 | 2 | 60 | |
| GSE54994 | CCDC89 | 220388 | 5 | 19 | 29 | |
| GSE60625 | CCDC89 | 220388 | 0 | 3 | 8 | |
| GSE74703 | CCDC89 | 220388 | 2 | 3 | 31 | |
| GSE74704 | CCDC89 | 220388 | 3 | 6 | 11 | |
| TCGA | CCDC89 | 220388 | 16 | 38 | 42 |
Total number of gains: 53; Total number of losses: 136; Total Number of normals: 299.
Somatic mutations of CCDC89:
Generating mutation plots.
Highly correlated genes for CCDC89:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCDC89 | TCEAL7 | 0.799554 | 3 | 0 | 3 |
| CCDC89 | ZCCHC18 | 0.711161 | 3 | 0 | 3 |
| CCDC89 | ZNF777 | 0.710908 | 4 | 0 | 3 |
| CCDC89 | CLCNKB | 0.708584 | 3 | 0 | 3 |
| CCDC89 | WDR60 | 0.708235 | 3 | 0 | 3 |
| CCDC89 | NACAD | 0.705163 | 3 | 0 | 3 |
| CCDC89 | POLL | 0.696413 | 3 | 0 | 3 |
| CCDC89 | CARD8 | 0.695264 | 3 | 0 | 3 |
| CCDC89 | CCDC81 | 0.69419 | 3 | 0 | 3 |
| CCDC89 | TMCO3 | 0.691636 | 4 | 0 | 3 |
| CCDC89 | NPR2 | 0.687638 | 4 | 0 | 3 |
| CCDC89 | FUZ | 0.671127 | 4 | 0 | 3 |
| CCDC89 | ZNF230 | 0.664821 | 4 | 0 | 3 |
| CCDC89 | MAGEL2 | 0.663962 | 4 | 0 | 4 |
| CCDC89 | SEMA5A | 0.652134 | 3 | 0 | 3 |
| CCDC89 | TPO | 0.64905 | 3 | 0 | 3 |
| CCDC89 | RBM43 | 0.647689 | 4 | 0 | 3 |
| CCDC89 | STS | 0.642098 | 3 | 0 | 3 |
| CCDC89 | USP27X | 0.638222 | 4 | 0 | 3 |
| CCDC89 | LILRA3 | 0.636808 | 3 | 0 | 3 |
For details and further investigation, click here
