SOHLH2

 

Full name: spermatogenesis and oogenesis specific basic helix-loop-helix 2 Alias Symbol: FLJ20449|TEB1|bHLHe81|SPATA28
Type: protein-coding gene Cytoband: 13q13.3
Entrez ID: 54937 HGNC ID: HGNC:26026 Ensembl Gene: ENSG00000120669 OMIM ID: 616066
Drug and gene relationship at DGIdb

 

Expression of SOHLH2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SOHLH2 54937 1555401_at 0.2275 0.5110
GSE26886 SOHLH2 54937 1555401_at -0.0218 0.8919
GSE45670 SOHLH2 54937 1555401_at 0.2508 0.0746
GSE53622 SOHLH2 54937 101026 -0.3188 0.2086
GSE53624 SOHLH2 54937 101026 0.3053 0.2477
GSE63941 SOHLH2 54937 1555401_at 0.2743 0.5310
GSE77861 SOHLH2 54937 1555401_at -0.0020 0.9887
SRP133303 SOHLH2 54937 RNAseq 0.0631 0.7666
SRP159526 SOHLH2 54937 RNAseq 2.4187 0.0061
SRP219564 SOHLH2 54937 RNAseq -0.9371 0.1546
TCGA SOHLH2 54937 RNAseq 0.1313 0.8433

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SOHLH2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SOHLH2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SOHLH2 54937 0 16 14
GSE20123 SOHLH2 54937 0 15 15
GSE43470 SOHLH2 54937 2 13 28
GSE46452 SOHLH2 54937 0 33 26
GSE47630 SOHLH2 54937 2 27 11
GSE54993 SOHLH2 54937 12 2 56
GSE54994 SOHLH2 54937 1 17 35
GSE60625 SOHLH2 54937 0 3 8
GSE74703 SOHLH2 54937 2 10 24
GSE74704 SOHLH2 54937 0 12 8
TCGA SOHLH2 54937 7 40 49

Total number of gains: 26; Total number of losses: 188; Total Number of normals: 274.  

 

Somatic mutations of SOHLH2:

 

Generating mutation plots.

 

Highly correlated genes for SOHLH2:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SOHLH2CGA0.666476403
SOHLH2UBOX50.645478303
SOHLH2PRR90.63342303
SOHLH2ITPA0.594872303
SOHLH2GTSF10.594393403
SOHLH2NAV30.566906303
SOHLH2VN1R20.555543403

For details and further investigation, click here