VN1R2

 

Full name: vomeronasal 1 receptor 2 Alias Symbol: V1RL2
Type: protein-coding gene Cytoband: 19q13.42
Entrez ID: 317701 HGNC ID: HGNC:19872 Ensembl Gene: ENSG00000196131 OMIM ID: 
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of VN1R2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 VN1R2 317701 1553549_at -0.0291 0.9233
GSE26886 VN1R2 317701 1553549_at -0.0397 0.7587
GSE45670 VN1R2 317701 1553549_at 0.0553 0.5664
GSE53622 VN1R2 317701 60966 0.0883 0.5398
GSE53624 VN1R2 317701 60966 0.0138 0.7670
GSE63941 VN1R2 317701 1553549_at 0.0529 0.6998
GSE77861 VN1R2 317701 1553549_at 0.0097 0.9390
SRP133303 VN1R2 317701 RNAseq -0.2131 0.1058
SRP159526 VN1R2 317701 RNAseq 0.3368 0.4747
SRP193095 VN1R2 317701 RNAseq 0.0476 0.7749
SRP219564 VN1R2 317701 RNAseq -0.7573 0.0797

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by VN1R2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of VN1R2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 VN1R2 317701 3 4 23
GSE20123 VN1R2 317701 3 3 24
GSE43470 VN1R2 317701 2 11 30
GSE46452 VN1R2 317701 45 1 13
GSE47630 VN1R2 317701 8 6 26
GSE54993 VN1R2 317701 17 4 49
GSE54994 VN1R2 317701 4 14 35
GSE60625 VN1R2 317701 9 0 2
GSE74703 VN1R2 317701 2 7 27
GSE74704 VN1R2 317701 3 1 16
TCGA VN1R2 317701 18 17 61

Total number of gains: 114; Total number of losses: 68; Total Number of normals: 306.  


 

Somatic mutations of VN1R2:

 

Generating mutation plots.

 

Highly correlated genes for VN1R2:

 

Showing all 14 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
VN1R2MS4A6E0.667837303
VN1R2CHRNA20.642302403
VN1R2PTPRT0.626574303
VN1R2LINC013520.624156303
VN1R2LUZP40.619529303
VN1R2SPINT30.59764503
VN1R2C9orf1350.585542303
VN1R2C14orf1780.561463303
VN1R2TTLL20.557048403
VN1R2SOHLH20.555543403
VN1R2OR8D20.550605303
VN1R2KIF5A0.543915403
VN1R2IL1RAPL20.536826503
VN1R2KRTAP11-10.524848403

For details and further investigation, click here