| Full name: neuron navigator 3 | Alias Symbol: KIAA0938|POMFIL1 | ||
| Type: protein-coding gene | Cytoband: 12q21.2 | ||
| Entrez ID: 89795 | HGNC ID: HGNC:15998 | Ensembl Gene: ENSG00000067798 | OMIM ID: 611629 |
| Drug and gene relationship at DGIdb | |||
Expression of NAV3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAV3 | 89795 | 204823_at | 0.2218 | 0.8495 | |
| GSE20347 | NAV3 | 89795 | 204823_at | 0.3639 | 0.0992 | |
| GSE23400 | NAV3 | 89795 | 204823_at | 0.0326 | 0.6226 | |
| GSE26886 | NAV3 | 89795 | 204823_at | 0.9299 | 0.0439 | |
| GSE29001 | NAV3 | 89795 | 204823_at | 0.3151 | 0.5025 | |
| GSE38129 | NAV3 | 89795 | 204823_at | 0.0748 | 0.7825 | |
| GSE45670 | NAV3 | 89795 | 204823_at | -0.5389 | 0.3483 | |
| GSE53622 | NAV3 | 89795 | 102341 | 0.4486 | 0.0235 | |
| GSE53624 | NAV3 | 89795 | 60821 | 0.4448 | 0.0344 | |
| GSE63941 | NAV3 | 89795 | 204823_at | -4.9475 | 0.0001 | |
| GSE77861 | NAV3 | 89795 | 204823_at | 0.5111 | 0.1943 | |
| GSE97050 | NAV3 | 89795 | A_33_P3336273 | -0.3099 | 0.3488 | |
| SRP007169 | NAV3 | 89795 | RNAseq | 2.4995 | 0.0017 | |
| SRP008496 | NAV3 | 89795 | RNAseq | 4.2191 | 0.0000 | |
| SRP064894 | NAV3 | 89795 | RNAseq | 0.5373 | 0.1677 | |
| SRP133303 | NAV3 | 89795 | RNAseq | 0.4053 | 0.2669 | |
| SRP159526 | NAV3 | 89795 | RNAseq | 0.3580 | 0.5212 | |
| SRP193095 | NAV3 | 89795 | RNAseq | 2.0180 | 0.0000 | |
| SRP219564 | NAV3 | 89795 | RNAseq | -0.0852 | 0.8976 | |
| TCGA | NAV3 | 89795 | RNAseq | 0.2393 | 0.3476 |
Upregulated datasets: 3; Downregulated datasets: 1.
Survival by NAV3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAV3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAV3 | 89795 | 3 | 3 | 24 | |
| GSE20123 | NAV3 | 89795 | 3 | 3 | 24 | |
| GSE43470 | NAV3 | 89795 | 3 | 1 | 39 | |
| GSE46452 | NAV3 | 89795 | 8 | 1 | 50 | |
| GSE47630 | NAV3 | 89795 | 10 | 1 | 29 | |
| GSE54993 | NAV3 | 89795 | 0 | 5 | 65 | |
| GSE54994 | NAV3 | 89795 | 7 | 1 | 45 | |
| GSE60625 | NAV3 | 89795 | 0 | 0 | 11 | |
| GSE74703 | NAV3 | 89795 | 3 | 1 | 32 | |
| GSE74704 | NAV3 | 89795 | 2 | 2 | 16 | |
| TCGA | NAV3 | 89795 | 14 | 14 | 68 |
Total number of gains: 53; Total number of losses: 32; Total Number of normals: 403.
Somatic mutations of NAV3:
Generating mutation plots.
Highly correlated genes for NAV3:
Showing top 20/154 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAV3 | PKDCC | 0.80671 | 3 | 0 | 3 |
| NAV3 | AMPH | 0.710768 | 3 | 0 | 3 |
| NAV3 | SHROOM1 | 0.696227 | 3 | 0 | 3 |
| NAV3 | TUBAL3 | 0.694235 | 4 | 0 | 3 |
| NAV3 | RASSF1 | 0.688124 | 3 | 0 | 3 |
| NAV3 | KLHL26 | 0.677697 | 3 | 0 | 3 |
| NAV3 | FAT4 | 0.665752 | 5 | 0 | 4 |
| NAV3 | MAGEE1 | 0.659483 | 3 | 0 | 3 |
| NAV3 | OBSL1 | 0.656739 | 3 | 0 | 3 |
| NAV3 | SUGCT | 0.656192 | 7 | 0 | 6 |
| NAV3 | NPR2 | 0.647005 | 6 | 0 | 5 |
| NAV3 | EML6 | 0.644337 | 3 | 0 | 3 |
| NAV3 | CHSY3 | 0.63971 | 6 | 0 | 6 |
| NAV3 | APBB2 | 0.638092 | 8 | 0 | 5 |
| NAV3 | BAHCC1 | 0.635434 | 5 | 0 | 5 |
| NAV3 | LINC01137 | 0.635302 | 4 | 0 | 3 |
| NAV3 | AP1S1 | 0.629084 | 4 | 0 | 4 |
| NAV3 | CPQ | 0.624988 | 4 | 0 | 3 |
| NAV3 | TBX3 | 0.624726 | 4 | 0 | 3 |
| NAV3 | NPW | 0.624009 | 3 | 0 | 3 |
For details and further investigation, click here
