| Full name: U-box domain containing 5 | Alias Symbol: UIP5|KIAA0860|Ubce7ip5|RNF37 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 22888 | HGNC ID: HGNC:17777 | Ensembl Gene: ENSG00000185019 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of UBOX5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UBOX5 | 22888 | 215544_s_at | 0.1270 | 0.6272 | |
| GSE20347 | UBOX5 | 22888 | 204598_at | 0.0732 | 0.5149 | |
| GSE23400 | UBOX5 | 22888 | 204598_at | -0.0896 | 0.0102 | |
| GSE26886 | UBOX5 | 22888 | 204598_at | 0.3003 | 0.0201 | |
| GSE29001 | UBOX5 | 22888 | 204598_at | -0.0164 | 0.9368 | |
| GSE38129 | UBOX5 | 22888 | 204598_at | -0.0699 | 0.4909 | |
| GSE45670 | UBOX5 | 22888 | 204598_at | -0.1086 | 0.2259 | |
| GSE53622 | UBOX5 | 22888 | 43553 | -0.4437 | 0.0006 | |
| GSE53624 | UBOX5 | 22888 | 43553 | 0.0110 | 0.9088 | |
| GSE63941 | UBOX5 | 22888 | 204598_at | 0.7359 | 0.0029 | |
| GSE77861 | UBOX5 | 22888 | 204598_at | 0.0297 | 0.8168 | |
| SRP007169 | UBOX5 | 22888 | RNAseq | -1.8516 | 0.0001 | |
| SRP008496 | UBOX5 | 22888 | RNAseq | -1.1544 | 0.0024 | |
| SRP064894 | UBOX5 | 22888 | RNAseq | -0.0240 | 0.9077 | |
| SRP133303 | UBOX5 | 22888 | RNAseq | -0.1919 | 0.1134 | |
| SRP159526 | UBOX5 | 22888 | RNAseq | 0.0381 | 0.8094 | |
| SRP193095 | UBOX5 | 22888 | RNAseq | 0.0692 | 0.5232 | |
| SRP219564 | UBOX5 | 22888 | RNAseq | 0.2110 | 0.4674 | |
| TCGA | UBOX5 | 22888 | RNAseq | -0.0939 | 0.1381 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by UBOX5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UBOX5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UBOX5 | 22888 | 12 | 3 | 15 | |
| GSE20123 | UBOX5 | 22888 | 13 | 3 | 14 | |
| GSE43470 | UBOX5 | 22888 | 10 | 1 | 32 | |
| GSE46452 | UBOX5 | 22888 | 26 | 1 | 32 | |
| GSE47630 | UBOX5 | 22888 | 18 | 4 | 18 | |
| GSE54993 | UBOX5 | 22888 | 2 | 14 | 54 | |
| GSE54994 | UBOX5 | 22888 | 24 | 2 | 27 | |
| GSE60625 | UBOX5 | 22888 | 0 | 0 | 11 | |
| GSE74703 | UBOX5 | 22888 | 9 | 1 | 26 | |
| GSE74704 | UBOX5 | 22888 | 8 | 1 | 11 | |
| TCGA | UBOX5 | 22888 | 40 | 11 | 45 |
Total number of gains: 162; Total number of losses: 41; Total Number of normals: 285.
Somatic mutations of UBOX5:
Generating mutation plots.
Highly correlated genes for UBOX5:
Showing top 20/184 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UBOX5 | C9orf16 | 0.738132 | 3 | 0 | 3 |
| UBOX5 | SLC8B1 | 0.668655 | 3 | 0 | 3 |
| UBOX5 | TNK1 | 0.668019 | 4 | 0 | 4 |
| UBOX5 | YBX2 | 0.657079 | 4 | 0 | 4 |
| UBOX5 | PARD6A | 0.652983 | 4 | 0 | 4 |
| UBOX5 | ANAPC2 | 0.647075 | 3 | 0 | 3 |
| UBOX5 | VAC14 | 0.646948 | 3 | 0 | 3 |
| UBOX5 | SOHLH2 | 0.645478 | 3 | 0 | 3 |
| UBOX5 | C10orf95 | 0.635197 | 4 | 0 | 4 |
| UBOX5 | GPR1-AS | 0.633877 | 3 | 0 | 3 |
| UBOX5 | MYL1 | 0.628401 | 3 | 0 | 3 |
| UBOX5 | SOGA1 | 0.623696 | 5 | 0 | 4 |
| UBOX5 | RBM19 | 0.614034 | 3 | 0 | 3 |
| UBOX5 | ARVCF | 0.611348 | 5 | 0 | 4 |
| UBOX5 | CST2 | 0.608983 | 4 | 0 | 3 |
| UBOX5 | PRAMEF12 | 0.604245 | 5 | 0 | 4 |
| UBOX5 | KLK14 | 0.603977 | 4 | 0 | 3 |
| UBOX5 | LMAN1L | 0.597508 | 5 | 0 | 5 |
| UBOX5 | RAB3IL1 | 0.595431 | 5 | 0 | 5 |
| UBOX5 | DNASE1L2 | 0.593715 | 4 | 0 | 3 |
For details and further investigation, click here
