GTSF1

 

Full name: gametocyte specific factor 1 Alias Symbol: FLJ32942|Cue110
Type: protein-coding gene Cytoband: 12q13.13
Entrez ID: 121355 HGNC ID: HGNC:26565 Ensembl Gene: ENSG00000170627 OMIM ID: 617484
Drug and gene relationship at DGIdb

 

Expression of GTSF1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GTSF1 121355 227711_at 1.3256 0.5161
GSE26886 GTSF1 121355 227711_at 1.5561 0.0221
GSE45670 GTSF1 121355 227711_at 2.1003 0.0452
GSE53622 GTSF1 121355 33490 0.7488 0.0717
GSE53624 GTSF1 121355 33490 1.1694 0.0002
GSE63941 GTSF1 121355 227711_at 3.6018 0.2163
GSE77861 GTSF1 121355 227711_at -0.6141 0.1982
GSE97050 GTSF1 121355 A_33_P3388192 0.5889 0.2798
TCGA GTSF1 121355 RNAseq 2.9142 0.0004

Upregulated datasets: 4; Downregulated datasets: 0.  


 

Survival by GTSF1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GTSF1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GTSF1 121355 4 1 25
GSE20123 GTSF1 121355 4 1 25
GSE43470 GTSF1 121355 3 0 40
GSE46452 GTSF1 121355 7 1 51
GSE47630 GTSF1 121355 10 2 28
GSE54993 GTSF1 121355 0 5 65
GSE54994 GTSF1 121355 4 1 48
GSE60625 GTSF1 121355 0 0 11
GSE74703 GTSF1 121355 3 0 33
GSE74704 GTSF1 121355 3 1 16
TCGA GTSF1 121355 16 11 69

Total number of gains: 54; Total number of losses: 23; Total Number of normals: 411.  


 

Somatic mutations of GTSF1:

 

Generating mutation plots.

 

Highly correlated genes for GTSF1:

 

Showing top 20/30 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GTSF1FOXC20.712548303
GTSF1C1orf740.65018303
GTSF1MAGEA120.636086606
GTSF1SEC61G0.629497303
GTSF1GPR1760.61178503
GTSF1TNC0.608801303
GTSF1TNFRSF10B0.60183303
GTSF1HMGA20.601729403
GTSF1SOHLH20.594393403
GTSF1AHR0.591813403
GTSF1CNTNAP50.589989303
GTSF1SFR10.5887303
GTSF1HIF1A0.565271403
GTSF1MAGEA10.563134804
GTSF1B3GNT50.560422303
GTSF1FLT10.560004303
GTSF1MAGEA60.55772806
GTSF1SCN8A0.555149303
GTSF1TMEM86B0.552015303
GTSF1PTHLH0.551401403

For details and further investigation, click here