TMCO5A

 

Full name: transmembrane and coiled-coil domains 5A Alias Symbol: MGC35118
Type: protein-coding gene Cytoband: 15q14
Entrez ID: 145942 HGNC ID: HGNC:28558 Ensembl Gene: ENSG00000166069 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of TMCO5A:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TMCO5A 145942 1553637_s_at -0.0386 0.8977
GSE26886 TMCO5A 145942 1553637_s_at 0.1299 0.2040
GSE45670 TMCO5A 145942 1553637_s_at 0.0120 0.9066
GSE53622 TMCO5A 145942 109317 -0.0105 0.9293
GSE53624 TMCO5A 145942 109317 0.1491 0.0614
GSE63941 TMCO5A 145942 1553637_s_at 0.0144 0.9268
GSE77861 TMCO5A 145942 1553637_s_at -0.0337 0.7070
SRP133303 TMCO5A 145942 RNAseq 0.6005 0.0740
TCGA TMCO5A 145942 RNAseq -2.3306 0.2029

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by TMCO5A expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TMCO5A:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TMCO5A 145942 2 6 22
GSE20123 TMCO5A 145942 2 6 22
GSE43470 TMCO5A 145942 4 4 35
GSE46452 TMCO5A 145942 3 7 49
GSE47630 TMCO5A 145942 8 11 21
GSE54993 TMCO5A 145942 4 6 60
GSE54994 TMCO5A 145942 5 7 41
GSE60625 TMCO5A 145942 4 0 7
GSE74703 TMCO5A 145942 4 4 28
GSE74704 TMCO5A 145942 1 5 14
TCGA TMCO5A 145942 11 18 67

Total number of gains: 48; Total number of losses: 74; Total Number of normals: 366.  

 

Somatic mutations of TMCO5A:

 

Generating mutation plots.

 

Highly correlated genes for TMCO5A:

 

Showing all 8 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TMCO5AGPR620.63678303
TMCO5ACOLEC100.602442303
TMCO5ATAL20.550482303
TMCO5ACDKL20.547334303
TMCO5AC20orf850.535358403
TMCO5AIFNA140.516173403
TMCO5AANO70.514004503
TMCO5ATINAG0.502934403

For details and further investigation, click here