| Full name: TAL bHLH transcription factor 2 | Alias Symbol: bHLHa19 | ||
| Type: protein-coding gene | Cytoband: 9q31.2 | ||
| Entrez ID: 6887 | HGNC ID: HGNC:11557 | Ensembl Gene: ENSG00000186051 | OMIM ID: 186855 |
| Drug and gene relationship at DGIdb | |||
Expression of TAL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAL2 | 6887 | 231759_at | 0.0486 | 0.9105 | |
| GSE26886 | TAL2 | 6887 | 231759_at | 0.1863 | 0.1516 | |
| GSE45670 | TAL2 | 6887 | 231759_at | -0.1451 | 0.1579 | |
| GSE53622 | TAL2 | 6887 | 59432 | -0.1629 | 0.1791 | |
| GSE53624 | TAL2 | 6887 | 59432 | 0.1051 | 0.2218 | |
| GSE63941 | TAL2 | 6887 | 231759_at | 0.5612 | 0.0065 | |
| GSE77861 | TAL2 | 6887 | 231759_at | -0.1480 | 0.2798 | |
| TCGA | TAL2 | 6887 | RNAseq | 0.6597 | 0.3832 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAL2 | 6887 | 4 | 10 | 16 | |
| GSE20123 | TAL2 | 6887 | 5 | 9 | 16 | |
| GSE43470 | TAL2 | 6887 | 7 | 3 | 33 | |
| GSE46452 | TAL2 | 6887 | 6 | 13 | 40 | |
| GSE47630 | TAL2 | 6887 | 1 | 17 | 22 | |
| GSE54993 | TAL2 | 6887 | 3 | 3 | 64 | |
| GSE54994 | TAL2 | 6887 | 9 | 10 | 34 | |
| GSE60625 | TAL2 | 6887 | 0 | 0 | 11 | |
| GSE74703 | TAL2 | 6887 | 6 | 3 | 27 | |
| GSE74704 | TAL2 | 6887 | 2 | 6 | 12 | |
| TCGA | TAL2 | 6887 | 26 | 20 | 50 |
Total number of gains: 69; Total number of losses: 94; Total Number of normals: 325.
Somatic mutations of TAL2:
Generating mutation plots.
Highly correlated genes for TAL2:
Showing top 20/80 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAL2 | GATA1 | 0.704211 | 3 | 0 | 3 |
| TAL2 | RGMB-AS1 | 0.677575 | 3 | 0 | 3 |
| TAL2 | CAMK2N2 | 0.676194 | 3 | 0 | 3 |
| TAL2 | GLRA2 | 0.674234 | 3 | 0 | 3 |
| TAL2 | FOXP3 | 0.666765 | 3 | 0 | 3 |
| TAL2 | DGKK | 0.643833 | 4 | 0 | 4 |
| TAL2 | WNT6 | 0.641231 | 3 | 0 | 3 |
| TAL2 | PRB4 | 0.640312 | 4 | 0 | 4 |
| TAL2 | PRAMEF11 | 0.636465 | 4 | 0 | 3 |
| TAL2 | LINC00491 | 0.620687 | 3 | 0 | 3 |
| TAL2 | DAO | 0.619057 | 3 | 0 | 3 |
| TAL2 | PCAT4 | 0.614477 | 3 | 0 | 3 |
| TAL2 | SIX3 | 0.608622 | 3 | 0 | 3 |
| TAL2 | FSCB | 0.607932 | 3 | 0 | 3 |
| TAL2 | NCKAP5L | 0.606899 | 4 | 0 | 3 |
| TAL2 | ESR1 | 0.593464 | 3 | 0 | 3 |
| TAL2 | CA14 | 0.589543 | 4 | 0 | 3 |
| TAL2 | ABHD1 | 0.585587 | 4 | 0 | 3 |
| TAL2 | AMBN | 0.583267 | 4 | 0 | 3 |
| TAL2 | CASC11 | 0.581809 | 4 | 0 | 3 |
For details and further investigation, click here
