| Full name: anoctamin 7 | Alias Symbol: NGEP|PCANAP5L|IPCA-5 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 50636 | HGNC ID: HGNC:31677 | Ensembl Gene: ENSG00000146205 | OMIM ID: 605096 |
| Drug and gene relationship at DGIdb | |||
Expression of ANO7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO7 | 50636 | 241918_at | -0.0996 | 0.7012 | |
| GSE26886 | ANO7 | 50636 | 241918_at | 0.1897 | 0.1064 | |
| GSE45670 | ANO7 | 50636 | 241918_at | -0.0577 | 0.5001 | |
| GSE53622 | ANO7 | 50636 | 35731 | 0.1286 | 0.1428 | |
| GSE53624 | ANO7 | 50636 | 35731 | -0.2133 | 0.0462 | |
| GSE63941 | ANO7 | 50636 | 241918_at | 0.1872 | 0.1886 | |
| GSE77861 | ANO7 | 50636 | 241918_at | -0.0089 | 0.9389 | |
| GSE97050 | ANO7 | 50636 | A_23_P335495 | -0.1516 | 0.4193 | |
| SRP064894 | ANO7 | 50636 | RNAseq | -1.0057 | 0.0163 | |
| SRP133303 | ANO7 | 50636 | RNAseq | -0.5298 | 0.1210 | |
| SRP159526 | ANO7 | 50636 | RNAseq | 1.0446 | 0.0609 | |
| SRP193095 | ANO7 | 50636 | RNAseq | -0.6377 | 0.1315 | |
| SRP219564 | ANO7 | 50636 | RNAseq | 0.1393 | 0.7245 | |
| TCGA | ANO7 | 50636 | RNAseq | -1.3847 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ANO7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANO7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO7 | 50636 | 1 | 12 | 17 | |
| GSE20123 | ANO7 | 50636 | 1 | 12 | 17 | |
| GSE43470 | ANO7 | 50636 | 1 | 9 | 33 | |
| GSE46452 | ANO7 | 50636 | 0 | 5 | 54 | |
| GSE47630 | ANO7 | 50636 | 4 | 5 | 31 | |
| GSE54993 | ANO7 | 50636 | 4 | 3 | 63 | |
| GSE54994 | ANO7 | 50636 | 8 | 9 | 36 | |
| GSE60625 | ANO7 | 50636 | 0 | 3 | 8 | |
| GSE74703 | ANO7 | 50636 | 1 | 7 | 28 | |
| GSE74704 | ANO7 | 50636 | 1 | 5 | 14 | |
| TCGA | ANO7 | 50636 | 12 | 28 | 56 |
Total number of gains: 33; Total number of losses: 98; Total Number of normals: 357.
Somatic mutations of ANO7:
Generating mutation plots.
Highly correlated genes for ANO7:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO7 | TSSK3 | 0.782145 | 4 | 0 | 4 |
| ANO7 | PALM3 | 0.778547 | 3 | 0 | 3 |
| ANO7 | SCGN | 0.77732 | 4 | 0 | 4 |
| ANO7 | AQP4 | 0.768784 | 4 | 0 | 4 |
| ANO7 | RALYL | 0.764074 | 3 | 0 | 3 |
| ANO7 | OR2B11 | 0.752113 | 3 | 0 | 3 |
| ANO7 | SLC19A3 | 0.747775 | 3 | 0 | 3 |
| ANO7 | PLA2G12B | 0.745231 | 4 | 0 | 4 |
| ANO7 | NXNL1 | 0.744242 | 3 | 0 | 3 |
| ANO7 | TMEM229A | 0.743557 | 3 | 0 | 3 |
| ANO7 | YY2 | 0.740906 | 3 | 0 | 3 |
| ANO7 | OR2T1 | 0.736464 | 3 | 0 | 3 |
| ANO7 | BSX | 0.733485 | 3 | 0 | 3 |
| ANO7 | BBC3 | 0.731714 | 3 | 0 | 3 |
| ANO7 | ACSM2B | 0.727914 | 3 | 0 | 3 |
| ANO7 | OTUD5 | 0.721547 | 3 | 0 | 3 |
| ANO7 | SHISA8 | 0.721543 | 3 | 0 | 3 |
| ANO7 | TFE3 | 0.720097 | 4 | 0 | 4 |
| ANO7 | CYP17A1 | 0.713142 | 4 | 0 | 4 |
| ANO7 | FFAR1 | 0.707447 | 4 | 0 | 4 |
For details and further investigation, click here
